698378-76-6

698378-76-6 - Names and Identifiers

Name	ethyl 2,2-difluoro-2-(2-fluorophenyl)acetate
Synonyms	ethyl 2,2-difluoro-2-(2-fluorophenyl)acetate Benzeneacetic acid, α,α,2-trifluoro-, ethyl ester
CAS	698378-76-6

698378-76-6 - Physico-chemical Properties

Molecular Formula	C10H9O2F3
Molar Mass	218.17

698378-76-6 - Introduction

ethyl 2,2-difluoro-2-(2-fluorophenyl)acetate, chemical formula C10H8F4O2, is an organic compound. It is a colorless liquid at room temperature, with low volatility and strong fragrance. The following is detailed information about the compound:

Nature:
-Melting point:-20 ℃
-Boiling Point: 151-153 ℃
-Relative density: 1.374
-refractive index: 1.457-1.461
-Solubility: Soluble in organic solvents such as ether and alcohol

Use:
- ethyl 2,2-difluoro-2-(2-fluorophenyl)acetate is widely used as an intermediate for pesticides and insecticides, and is used to synthesize a variety of fluorine-containing organic compounds.
-It can also be used as a research reagent for medicine and agricultural chemicals.

Method:
ethyl 2,2-difluoro-2-(2-fluorophenyl)acetate can be synthesized by the following steps:
1. Reacting 2-fluorophenylacetic acid with cuprous fluoride to obtain 2-fluorophenylacetic acid;
2. Reacting the obtained 2-fluorophenylacetic acid with chloroacetic acid ester to generate the corresponding acid ethyl ester;
3. Finally, the acid ethyl ester is subjected to fluorination reaction in the presence of fluoride to obtain the final product.

Safety Information:
ethyl 2,2-difluoro-2-(2-fluorophenyl)acetate has low toxicity, but should still be handled in accordance with safe practices. During use, it is recommended to wear suitable protective equipment, such as gloves, goggles and protective clothing. Avoid contact with skin, eyes and inhalation of vapors. In case of accidental or accidental contact, seek medical assistance immediately.

Last Update：2024-04-09 21:00:56