697230-91-4
3aH-Indazol-3-amine, 4-fluoro-
CAS: 697230-91-4
Molecular Formula: C7H6FN3
697230-91-4 - Names and Identifiers
| Name | 3aH-Indazol-3-amine, 4-fluoro- |
| Synonyms | 4-Fluoro-3aH-indazol-3-amine 3aH-Indazol-3-amine, 4-fluoro- 3aH-Indazol-3-aMine, 4-fluoro- 3aH-Indazol-3-amine,4-fluoro-(9CI) |
| CAS | 697230-91-4 |
697230-91-4 - Physico-chemical Properties
| Molecular Formula | C7H6FN3 |
| Molar Mass | 151.14 |
| Density | 1.55±0.1 g/cm3(Predicted) |
| Boling Point | 290.5±50.0 °C(Predicted) |
| pKa | 6.53±0.40(Predicted) |
| Storage Condition | 2-8°C |
697230-91-4 - Introduction
3aH-Indazol-3-amine, 4-fluoro-is an organic compound with the chemical formula C7H6FN3. It is a white solid with a strong ammonia odor. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White solid.
-Solubility: Soluble in organic solvents, such as dimethyl amide, dichloromethane and ethanol.
-Melting point: approximately in the range of 160-165°C.
-Stability: relatively stable at room temperature, but avoid contact with oxidants.
Use:
3aH-Indazol-3-amine, 4-fluoro-is an intermediate compound commonly used in organic synthesis. It can be used as a raw material for the synthesis of compounds such as drugs, pesticides, pigments and dyes.
Preparation Method:
There are many ways to prepare 3aH-Indazol-3-amine, 4-fluoro-, the following is a common method:
1. First, the n-peralkylation reaction of p-nitroaniline and n-propionitrile at 0°C is used to generate the nitrogen cation of aniline.
2. Then, the generated nitrogen cation reacts with hydrogen fluoride to generate 3-fluoroaniline.
3. Finally, 3-fluoroaniline and indazole are subjected to amination reaction, and heated in the presence of hydrochloric acid to generate 3aH-Indazol-3-amine, 4-fluoro-.
Security Information:
- 3aH-Indazol-3-amine, 4-fluoro-may have a certain teratogenic effect on the human body, so it is necessary to follow certain safety operation specifications during use.
-Appropriate precautions such as gloves, goggles and protective clothing should be taken when handling the compound.
-Avoid contact with skin, eyes and mucous membranes. In case of contact, rinse immediately with plenty of water and seek medical help.
-During storage and use, avoid contact with oxidants and combustibles to prevent accidents such as fire or explosion.
- 3aH-Indazol-3-amine, 4-fluoro-should not be discharged directly into the environment and should be properly treated and disposed of to avoid pollution to the environment.
Nature:
-Appearance: White solid.
-Solubility: Soluble in organic solvents, such as dimethyl amide, dichloromethane and ethanol.
-Melting point: approximately in the range of 160-165°C.
-Stability: relatively stable at room temperature, but avoid contact with oxidants.
Use:
3aH-Indazol-3-amine, 4-fluoro-is an intermediate compound commonly used in organic synthesis. It can be used as a raw material for the synthesis of compounds such as drugs, pesticides, pigments and dyes.
Preparation Method:
There are many ways to prepare 3aH-Indazol-3-amine, 4-fluoro-, the following is a common method:
1. First, the n-peralkylation reaction of p-nitroaniline and n-propionitrile at 0°C is used to generate the nitrogen cation of aniline.
2. Then, the generated nitrogen cation reacts with hydrogen fluoride to generate 3-fluoroaniline.
3. Finally, 3-fluoroaniline and indazole are subjected to amination reaction, and heated in the presence of hydrochloric acid to generate 3aH-Indazol-3-amine, 4-fluoro-.
Security Information:
- 3aH-Indazol-3-amine, 4-fluoro-may have a certain teratogenic effect on the human body, so it is necessary to follow certain safety operation specifications during use.
-Appropriate precautions such as gloves, goggles and protective clothing should be taken when handling the compound.
-Avoid contact with skin, eyes and mucous membranes. In case of contact, rinse immediately with plenty of water and seek medical help.
-During storage and use, avoid contact with oxidants and combustibles to prevent accidents such as fire or explosion.
- 3aH-Indazol-3-amine, 4-fluoro-should not be discharged directly into the environment and should be properly treated and disposed of to avoid pollution to the environment.
Last Update：2024-04-09 21:01:54
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CAS: 697230-91-4
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CAS: 697230-91-4
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View History
697230-91-4
1-(3-Bromophenyl)-3-phenyl-5-methyl-1H-pyrazolo[4,3-c]quinolin-4(5H)-one
10-(1-Naphthyl)anthracene-9-boronic Acid Pinacol Ester
3-Thiophenecarboxylic acid, 2-amino-4-(2,5-dimethylphenyl)-, ethyl ester
5-(3-BROMOPHENYL)-1,3,4-OXADIAZOLE-2-THIOL
1-(5-chloro-pyridin-2-yl)-3-m-tolyl-urea
Trepirium
5-chloro-9,10,11,12-tetrahydro-8H-[1]benzothieno[2',3':4,5]pyrimido[2,1-a]phthalazin-8-one
3-({2-[(4-chlorophenyl)imino]-4-oxo-1,3-thiazolidin-5-ylidene}methyl)phenyl 4-(acetylamino)benzenesulfonate
B-[5-(Hydroxymethyl)-2-(trifluoromethyl)phenyl]boronic acid
1-(3-Bromophenyl)-3-phenyl-5-methyl-1H-pyrazolo[4,3-c]quinolin-4(5H)-one
10-(1-Naphthyl)anthracene-9-boronic Acid Pinacol Ester
3-Thiophenecarboxylic acid, 2-amino-4-(2,5-dimethylphenyl)-, ethyl ester
5-(3-BROMOPHENYL)-1,3,4-OXADIAZOLE-2-THIOL
1-(5-chloro-pyridin-2-yl)-3-m-tolyl-urea
Trepirium
5-chloro-9,10,11,12-tetrahydro-8H-[1]benzothieno[2',3':4,5]pyrimido[2,1-a]phthalazin-8-one
3-({2-[(4-chlorophenyl)imino]-4-oxo-1,3-thiazolidin-5-ylidene}methyl)phenyl 4-(acetylamino)benzenesulfonate
B-[5-(Hydroxymethyl)-2-(trifluoromethyl)phenyl]boronic acid