66335-37-3 - Names and Identifiers
Name | 5'-Deoxy-5-fluoro-2',3'-O-isopropylidene-D-cytidine
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Synonyms | 2',3'-O-isopropylidene-5'-Deoxy-5-F-cytidine 5'-Deoxy-5-fluoro-2',3'-O-isopropylidenecytidine 5'-Deoxy-2',3'-O-Isopropylidene-5-Fluoro-D-Cytidine 5'-Deoxy-5-fluoro-2',3'-O-isopropylidene-D-cytidine 5'-deoxy-5-fluoro-2',3'-O-(1-methylethylidene)cytidine cytidine, 5'-deoxy-5-fluoro-2',3'-O-(1-methylethylidene)- Cytidine, 5'-deoxy-5-fluoro-2',3'-O-(1-methylethylidene)- 4-amino-5-fluoro-1-(2,2,6-trimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-2-pyrimidinone
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CAS | 66335-37-3
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InChI | InChI=1/C12H16FN3O4/c1-5-7-8(20-12(2,3)19-7)10(18-5)16-4-6(13)9(14)15-11(16)17/h4-5,7-8,10H,1-3H3,(H2,14,15,17)/t5-,7-,8-,10-/m1/s1 |
66335-37-3 - Physico-chemical Properties
Molecular Formula | C12H16FN3O4
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Molar Mass | 285.27 |
Density | 1.63±0.1 g/cm3(Predicted) |
Boling Point | 384.1±52.0 °C(Predicted) |
Flash Point | 186.1°C |
Vapor Presure | 4.2E-06mmHg at 25°C |
pKa | 2.39±0.10(Predicted) |
Refractive Index | 1.652 |
Use | Capecitabine Intermediate |
66335-37-3 - Introduction
5 '-Deoxy-5-fluoro-2',3 '-O-isopropylidene-D-cytidine is an organic compound with the formula C12H15FN3O4. It is a deoxynucleoside analog with a structure similar to cytosine (cytidine) but with a fluorine atom at the 5 '-position and an isopropylidene (isopropylidene) group at the 2' and 3 'positions.
This compound has antiviral activity and can be used to treat certain viral infections, such as hepatitis B virus and human immunodeficiency virus (HIV). It can inhibit virus replication and transmission and help control the development of disease.
The method for preparing 5 '-Deoxy-5-fluoro-2',3 '-O-isopropylidene-D-cytidine is complicated and generally requires multi-step synthesis. Its preparation method can use chemical synthesis route, through different reaction steps to convert the appropriate precursor compound into the target product.
For safety information, 5 '-Deoxy-5-fluoro-2',3 '-O-isopropylidene-D-cytidine should be stored in sealed containers and kept dry and protected from light. Appropriate protective equipment, such as gloves and glasses, should be worn during use. In addition, it may be toxic to the environment and its discharge into water bodies or soil should be avoided. Relevant safe practices and reasonable laboratory practices should be followed in use and handling.
Last Update:2024-04-10 22:29:15