(1R,5S)-5-(Dimethylphenylsilyl)-2-hydroxymethyl-2-cyclopentene-1-carboxylic acid is an organic compound with the following properties:
-Appearance: Colorless liquid or solid
-Molecular formula: C15H20O3Si
-Molecular weight: 276.41g/mol
-Melting point: about 40-42°C
-Boiling point: about 330°C
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide
(1R,5S)-5-(dimethylphenylsilyl)-2-hydroxymethyl-2-cyclopentene-1-carboxylic acid is mainly used in organic synthesis as a catalyst, reaction intermediate or pharmaceutical synthesis raw material.
The method for preparing (1R,5S)-5-(dimethylphenylsilyl)-2-hydroxymethyl-2-cyclopentene-1-carboxylic acid is generally carried out by the following steps:
1.2-Methyl -2-cyclopentene -1-one was obtained as a raw material.
2. 2-Methyl-2-cyclopenten-1-one is reacted with trimethylfluorosilane by heating reaction to obtain 2-methyl-5-trimethylsilyl-2-cyclopenten-1-one.
3. A reaction characterized by redox is carried out under alkaline conditions to obtain (1R,5S)-5-(dimethylphenylsilyl)-2-cyclopentene-1-carboxylic acid from 2-methyl-5-trimethylsilyl-2-cyclopentene-1-one.
Regarding safety information,(1R,5S)-5-(dimethylphenylsilyl)-2-hydroxymethyl-2-cyclopentene-1-carboxylic acid is irritating and should be used to avoid direct contact with skin, eyes and respiratory tract. Operate in a well-ventilated area and wear appropriate protective equipment.