production method | aniline is used to react with ethylene oxide in the presence of acetic acid at room temperature, and N is formed by hydroxyethylation, N-bis (2-hydroxyethyl) aniline, then phosphorus oxychloride, dimethyl formamide formylation, nitrogen mustard benzaldehyde, and then with the horse urea acid in the role of potassium bicarbonate ring, 4-{4-[N,N-bis (2-chloroethyl) amino] benzylidene}-2-phenyloxazolin-5-one is obtained. The latter is reduced with zinc dust-hydrochloric acid and ring-opening gives the product. |