6-Cyano-2-quinolone - Names and Identifiers
6-Cyano-2-quinolone - Physico-chemical Properties
Molecular Formula | C10H6N2O
|
Molar Mass | 170.17 |
Density | 1.32g/cm3 |
Boling Point | 420.2°C at 760 mmHg |
Flash Point | 207.9°C |
Vapor Presure | 2.86E-07mmHg at 25°C |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.651 |
6-Cyano-2-quinolone - Introduction
6-cyanoquinolin-2(1H)-one is an organic compound with the chemical formula C10H6N2O. The following is a description of the properties, uses, preparation and safety information of 6-cyanoquinolin-2(1H)-one:
Nature:
-Appearance: 6-cyanoquinolin-2(1H)-one is a white crystalline solid.
-Melting point: about 140-142 degrees Celsius.
-Solubility: Soluble in some organic solvents, such as chloroform, dimethyl sulfoxide and methanol.
Use:
-Chemical research: 6-cyanoquinolin-2(1H)-one is commonly used as an intermediate for the synthesis of other compounds. It can participate in a variety of organic reactions, such as cyanation reactions, substitution reactions, etc.
-Drug research and development: Due to the special properties of its chemical structure, 6-cyanoquinolin-2(1H)-one may have some potential biological activities, so it may be used to synthesize and discover new drug molecules in drug research and development.
Preparation Method:
- 6-cyanoquinolin-2(1H)-one can be prepared by the reaction of benzimide and hydrazine. First, benzimide is hydrolyzed with acetic acid or acetic acid to obtain the corresponding acid, and then treated with thionyl chloride to obtain the intermediate, and finally reacted with hydrazine under alkaline conditions to obtain 6-cyanoquinolin-2(1H)-one.
Safety Information:
- 6-cyanoquinolin-2(1H)-one is less toxic and dangerous, but any chemical should be handled properly. When in use, wear appropriate personal protective equipment to avoid contact with skin and eyes.
-Store it in a sealed manner and avoid contact with oxidants or combustibles.
-When handling 6-cyanoquinolin-2(1H)-one, you should follow good laboratory safety procedures and comply with local chemical safety regulations.
Last Update:2024-04-09 21:01:54