6-Bromo-3-fluoropicoline
2-Bromo-5-fluoro-6-picoline
CAS: 374633-38-2
Molecular Formula: C6H5BrFN
6-Bromo-3-fluoropicoline - Names and Identifiers
| Name | 2-Bromo-5-fluoro-6-picoline |
| Synonyms | 6-Brom 6-Bromo-3-fluoropicoline 6-Bromo-3-fluoro-2-picoline 2-Bromo-5-fluoro-6-picoline 2-BROMO-5-FLUORO-6-PICOLINE 6-bromo-3-fluoro-2-methylpyridine 5-FLUORO-6-METHYL-2-BROMOPYRIDINE 6-BROMO-3-FLUORO-2-METHYLPYRIDINE 2-Bromo-5-fluoro-6-methylpyridine 2-BROMO-5-FLUORO-6-PICOLINE (2-BROMO-5-FLUORO-6-METHYLPYRIDINE) |
| CAS | 374633-38-2 |
| EINECS | 675-596-4 |
| InChI | InChI=1/C6H5BrFN/c1-4-5(8)2-3-6(7)9-4/h2-3H,1H3 |
6-Bromo-3-fluoropicoline - Physico-chemical Properties
| Molecular Formula | C6H5BrFN |
| Molar Mass | 190.01 |
| Density | 1.592±0.06 g/cm3(Predicted) |
| Melting Point | 63-65°C |
| Boling Point | 183.4±35.0 °C(Predicted) |
| Flash Point | 64.7°C |
| Vapor Presure | 1.06mmHg at 25°C |
| pKa | -0.91±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.529 |
6-Bromo-3-fluoropicoline - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
| Hazard Class | IRRITANT |
6-Bromo-3-fluoropicoline - Introduction
2-Bromo-5-fluoro-6-picoline is an organic compound with the chemical formula C7H6BrFN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless or light yellow liquid
-Molecular weight: 187.03g/mol
-Melting point:-48 ℃
-Boiling point: 200-202 ℃
-Density: 1.49 g/ml
-Solubility: Soluble in organic solvents such as alcohols and ethers
Use:
2-Bromo-5-fluoro-6-picoline is widely used in the field of organic synthesis, commonly used:
-intermediates in organic synthesis
-raw materials for drug synthesis
-Precursors of pesticides and insecticides
Preparation Method:
2-Bromo-5-fluoro-6-picoline can be prepared by the following methods:
-Add hydrogen bromide to the picoline solution, and then add boron trifluoride to react to generate 2-Bromo-5-fluoro-6-picoline
-Add sodium chloride and potassium bromide to picoline, and then add hydrogen bromide to react to generate 2-Bromo-5-fluoro-6-picoline
Safety Information:
- 2-Bromo-5-fluoro-6-picoline is flammable and needs to be kept away from fire and high temperature
-Pay attention to avoid contact with skin, eyes and respiratory tract during operation
-Wear appropriate protective equipment such as gloves, goggles and masks when using
-Waste should be disposed of in accordance with local laws and regulations to avoid environmental pollution.
Nature:
-Appearance: colorless or light yellow liquid
-Molecular weight: 187.03g/mol
-Melting point:-48 ℃
-Boiling point: 200-202 ℃
-Density: 1.49 g/ml
-Solubility: Soluble in organic solvents such as alcohols and ethers
Use:
2-Bromo-5-fluoro-6-picoline is widely used in the field of organic synthesis, commonly used:
-intermediates in organic synthesis
-raw materials for drug synthesis
-Precursors of pesticides and insecticides
Preparation Method:
2-Bromo-5-fluoro-6-picoline can be prepared by the following methods:
-Add hydrogen bromide to the picoline solution, and then add boron trifluoride to react to generate 2-Bromo-5-fluoro-6-picoline
-Add sodium chloride and potassium bromide to picoline, and then add hydrogen bromide to react to generate 2-Bromo-5-fluoro-6-picoline
Safety Information:
- 2-Bromo-5-fluoro-6-picoline is flammable and needs to be kept away from fire and high temperature
-Pay attention to avoid contact with skin, eyes and respiratory tract during operation
-Wear appropriate protective equipment such as gloves, goggles and masks when using
-Waste should be disposed of in accordance with local laws and regulations to avoid environmental pollution.
Last Update：2024-04-09 02:00:45
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View History
6-Bromo-3-fluoropicoline
BisTris chloride
6624-45-9
2-Methyl-3-nitro-4-pyridinamine
3,4,6-trichloro-5-methyl-Pyridazine
103429-63-6
2-Bromo-4-methyl-nicotinic acid ethyl ester
83846-68-8
1343785-00-1
252351-96-5
BisTris chloride
6624-45-9
2-Methyl-3-nitro-4-pyridinamine
3,4,6-trichloro-5-methyl-Pyridazine
103429-63-6
2-Bromo-4-methyl-nicotinic acid ethyl ester
83846-68-8
1343785-00-1
252351-96-5