Molecular Formula | C205H341N61O52 |
Molar Mass | 4492.27854 |
Appearance | buffered aqueous solution |
Storage Condition | -20°C |
introduction | there are two main types of antibacterial peptides produced in the human body: defensin family peptides and cathelicidin family peptides. Although there are many members of defensin family peptides, cathelicidin only one antibacterial peptide product LL-37. LL-37 is the C- terminal cleavage product of cathelicidin peptide Hcap-18, which can directly kill bacteria, fungi and viruses. |
action | LL-37 also play an immune regulatory role by chemotaxis of immune cells, regulating the secretion of inflammatory promoting factors/inhibiting factors, coordinating natural immunity and acquired immunity and other functions. LL-37 can also act on vascular endothelial cells and epithelial cells to stimulate angiogenesis and promote injury repair. In addition, uncontrolled regulation of LL-37 expression can also cause many diseases. For example, in psoriasis, the increase in LL-37 expression may promote autoimmune response. |