Molecular Formula | C12H18ClNO2 |
Molar Mass | 243.73 |
Storage Condition | -20℃ |
In vitro study | HOKU-81 (4-Hydroxytulobuterol) is approximately 8 times more potent than tulobuterol, approximately twice as potent as salbutamol, and approximately as potent as isoprenaline in relaxing effect on the isolated tracheal smooth muscle preparation of guinea pigs. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 4.103 ml | 20.515 ml | 41.029 ml |
5 mM | 0.821 ml | 4.103 ml | 8.206 ml |
10 mM | 0.41 ml | 2.051 ml | 4.103 ml |
5 mM | 0.082 ml | 0.41 ml | 0.821 ml |
biological activity | HOKU-81 (4-Hydroxytulobuterol) is one of the metabolites of Tulobuterol (HY-B1810). HOKU-81 is a potent and selective β2-adrenoceptor stimulator. HOKU-81 has the role of bronchiectasis. |