Name | 2,2'-(1-Methyl-2,6-piperidinediyl)diacetophenon |
Synonyms | Lobelanine Lobeline HCl EP Impurity B 1-Methyl-2,6-bisphenacylpiperidine 2,2'-(1-Methyl-2,6-piperidinediyl)diacetophenon 1-Methyl-2α,6α-bis[2-oxo-2-phenylethyl]piperidine 2,2'-(1-Methyl-2,6-piperidinediyl)bis(1-phenylethanone 2,2'-[(2β,6β)-1-Methyl-2,6-piperidinediyl]bis(1-phenylethanone) 2,2'-[(2α,6α)-1-Methyl-2,6-piperidinediyl]bis(1-phenylethanone) |
CAS | 579-21-5 |
Molecular Formula | C22H25NO2 |
Molar Mass | 335.44 |
Density | 1.1072 (rough estimate) |
Melting Point | 99° |
Boling Point | 472.07°C (rough estimate) |
pKa | 9.42±0.10(Predicted) |
Refractive Index | 1.5614 (estimate) |
Physical and Chemical Properties | Needle crystals (petroleum ether/ether). Melting point 172 ℃. Soluble in ethanol, acetone, benzene, chloroform, slightly soluble in water, ether. |
UN IDs | 1544 |
Hazard Class | 6.1(b) |
Packing Group | III |
Use | an intermediate of Lobeline hydrochloride. |
production method | the product can be prepared by reacting glutaraldehyde with potassium benzoylacetate and methylamine, and combining and condensing the ring. |