5605-46-9 - Names and Identifiers
Name | (2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol
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Synonyms | N-Tosylhydroxy-L-prolinol (3R)-5-(hydroxyMethyl)-1-tosylpyrrolidin-3-ol (3R,5S)-5-(hydroxymethyl)-1-tosylpyrrolidin-3-ol trans-(-)-4-Hydroxy-1-(p-tolylsulfonyl)pyrrolidine-2-methanol (2S,4R)-4-Hydro×y-1-[(4-Methylphenyl)sulfonyl]pyrrolidine-2-Methanol (2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol 2-Pyrrolidinemethanol, 4-hydroxy-1-[(4-methylphenyl)sulfonyl]-, (2S,4R)- ((2S-trans)-4-hydroxy-1-[(4-methoxyphenyl) sulfonyl]-2pyrrolidinemethanol
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CAS | 5605-46-9
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InChI | InChI=1S/C12H17NO4S/c1-9-2-4-12(5-3-9)18(16,17)13-7-11(15)6-10(13)8-14/h2-5,10-11,14-15H,6-8H2,1H3/t10-,11+/m0/s1 |
5605-46-9 - Physico-chemical Properties
Molecular Formula | C12H17NO4S
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Molar Mass | 271.33 |
Density | 1.364 |
Melting Point | 132-133℃ |
Storage Condition | 2-8°C |
5605-46-9 - Introduction
(2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol is an organic compound with the following properties and uses:
Nature:
-Appearance: White to light yellow solid
-Solubility: Soluble in organic solvents such as water, ethanol and chloroform
-Molecular formula: C13H19NO4S
-Molecular weight: 285.36g/mol
-Melting point: 101-104°C
-Refractive Index: 1.520
-specific rotation:-116 ° (c = 1, ethanol)
Use:
(2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol is an important chiral intermediate compound, which is commonly used in drug synthesis. It can be used to prepare antiviral drugs, anti-tumor drugs and antibacterial drugs.
Preparation Method:
The preparation method of
(2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol is relatively complicated and is mainly obtained by chemical synthesis. The specific synthetic route may vary depending on the reaction conditions and starting materials.
Safety Information:
(2S,4R)-4-Hydroxy-1-[(4-methylphenyl)sulfonyl]pyrrolidine-2-methanol has better safety, but as a chemical substance, the following matters should be paid attention to during use and storage:
-Avoid contact with skin and eyes. In case of contact, rinse with water immediately.
-Avoid inhaling dust or vapor and ensure that you operate in a well-ventilated environment.
-Storage should be sealed and kept away from fire and oxidizing agents.
-In case of misuse or inhalation, please seek medical attention immediately and provide the necessary information to the doctor with the relevant safety data sheet.
Last Update:2024-04-09 19:05:50