Name | Nimustine hydrochloride |
Synonyms | ACNU Cs-439 NIMUSTINE HCL Nimustine HCl(ACNU) NIMUSTINE HYDROCHLORIDE Nimustine hydrochloride 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosoureahydr 1-(2-cloroetil)-1-nitroso-3-((2-metil-4-aminopirimidin-5-il)metil)ureaclorhi 1-(4-AMINO-2-METHYL-5-PYRIMIDINYL)-METHYL-3-(2-CHLOROETHYL)-3-NITROSOUREA HYDROCHLORIDE 3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-1-(2-Chloroethyl)-1-Nitrosourea Hydrochloride N'-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-N-(2-CHLOROETHYL)-N-NITROSOUREA HYDROCHLORIDE 3-[(4-Amino-2-Methyl-Pyrimidin-5-Yl)Methyl]-1-(2-Chloroethyl)-1-Nitroso-Urea Hydrochloride |
CAS | 55661-38-6 52208-23-8 |
EINECS | 678-313-2 |
InChI | InChI=1/C9H13ClN6O2.ClH/c1-6-12-4-7(8(11)14-6)5-13-9(17)16(15-18)3-2-10;/h4H,2-3,5H2,1H3,(H,13,17)(H2,11,12,14);1H |
Molecular Formula | C9H14Cl2N6O2 |
Molar Mass | 309.15 |
Melting Point | 186°C(lit.) |
Solubility | soluble in Methanol |
Appearance | White to light yellow crystalline solid. |
Color | White to Light yellow |
Merck | 14,6553 |
PH | 3.0~4.5 (5g/l, 25℃) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
MDL | MFCD01676942 |
Use | Has anti-tumor effect, the degradation of DNA alkylation in cells, inhibition of DNA and RNA synthesis |
Hazard Symbols | T - Toxic |
Risk Codes | 25 - Toxic if swallowed |
Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 2811 |
RTECS | YR8450000 |
Hazard Class | 6.1 |
Packing Group | III |
Toxicity | LD50 in mice, rats (mg/kg): 62, 46 i.v. (Masuda) |