55325-48-9
5-Chlorotryptophan
CAS: 55325-48-9
Molecular Formula: C11H11ClN2O2
55325-48-9 - Names and Identifiers
| Name | 5-Chlorotryptophan |
| Synonyms | H-D-Trp(5-Cl)-OH 5-Chlorotryptophan D-5-ChloroTryptophan 5-CHLORO-D-TRYPTOPHAN 5-Chloro-DL-tryptophan D-Tryptophan, 5-chloro- DL-2-Amino-3(5-chloroindolyl)propionic acid 2-Amino-3-(5-chloro-1H-indol-3-yl)propanoic acid (R)-2-Amino-3-(5-chloro-1H-indol-3-yl)propanoic acid (2R)-2-amino-3-(5-chloro-1H-indol-3-yl)propanoic acid |
| CAS | 55325-48-9 |
| InChI | InChI=1S/C11H11ClN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16) |
55325-48-9 - Physico-chemical Properties
| Molecular Formula | C11H11ClN2O2 |
| Molar Mass | 238.67 |
| Density | 1.474±0.06 g/cm3(Predicted) |
| Boling Point | 476.9±45.0 °C(Predicted) |
| pKa | 2.21±0.10(Predicted) |
55325-48-9 - Introduction
5-Chlorotryptophan is an unnatural amino acid containing a chlorine atom. Its chemical name is L-2-Amino-3-(5-chroo-1H-indol-3-yl) propanoic acid.
In terms of properties, 5-Chlorotryptophan is a white crystal with a melting point of 227-229 degrees Celsius. It is almost insoluble in water, but soluble in some organic solvents such as ethanol and dimethyl sulfoxide.
In terms of application, 5-Chlorotryptophan is an important synthetic intermediate, commonly used in organic synthesis. It can be used to prepare other chlorotryptophan derivatives and chloropigments, and has a wide range of applications. At the same time, 5-Chlorotryptophan can also be used to study the tryptophan pathway metabolism and the relationship between protein structure and function.
Regarding the production method, 5-Chlorotryptophan can be obtained by reacting tryptophan with a chlorinating reagent. In general, 5-Chlorotryptophan can be prepared by reaction with tryptophan under appropriate conditions using thionyl chloride (thionyl chloride) or phosphorus oxychloride (phosphoryl chloride) as a chlorinating reagent.
In terms of safety information, 5-Chlorotryptophan is relatively safe under normal conditions, but it is still necessary to pay attention to its toxicity and corrosiveness. During use and handling, follow relevant safety procedures and wear appropriate protective equipment. In addition, it should be stored in a dry, well-ventilated place, away from heat and flammable materials. When disposing of waste, it should be disposed of in accordance with local regulations. To ensure safety, follow the relevant laboratory practices and guidelines.
In terms of properties, 5-Chlorotryptophan is a white crystal with a melting point of 227-229 degrees Celsius. It is almost insoluble in water, but soluble in some organic solvents such as ethanol and dimethyl sulfoxide.
In terms of application, 5-Chlorotryptophan is an important synthetic intermediate, commonly used in organic synthesis. It can be used to prepare other chlorotryptophan derivatives and chloropigments, and has a wide range of applications. At the same time, 5-Chlorotryptophan can also be used to study the tryptophan pathway metabolism and the relationship between protein structure and function.
Regarding the production method, 5-Chlorotryptophan can be obtained by reacting tryptophan with a chlorinating reagent. In general, 5-Chlorotryptophan can be prepared by reaction with tryptophan under appropriate conditions using thionyl chloride (thionyl chloride) or phosphorus oxychloride (phosphoryl chloride) as a chlorinating reagent.
In terms of safety information, 5-Chlorotryptophan is relatively safe under normal conditions, but it is still necessary to pay attention to its toxicity and corrosiveness. During use and handling, follow relevant safety procedures and wear appropriate protective equipment. In addition, it should be stored in a dry, well-ventilated place, away from heat and flammable materials. When disposing of waste, it should be disposed of in accordance with local regulations. To ensure safety, follow the relevant laboratory practices and guidelines.
Last Update：2024-04-09 21:49:45
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CAS: 55325-48-9
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CAS: 55325-48-9
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