Name | 4'-(Octyloxy)-4-biphenylcarbonitrile |
Synonyms | 4'-(Octyloxy)-4-cyanobiphenyl 4'-(n-Octyloxy)-4-cyanobiphenyl 4-(4-octyloxyphenyl)benzonitrile 4'-(Octyloxy)-4-biphenylcarbonitrile 1'-biphenyl]-4-carbonitrile,4'-(octyloxy)-[ 4'-(Octyloxy)[1,1'-biphenyl]-4-carbonitrile 1'-biphenyl)-4-carbonitrile,4'-(octyloxy)-( 1'-Biphenyl]-4-carbonitrile,4'-(octyloxy)-[1 [1,1'-Biphenyl]-4-carbonitrile, 4'-(octyloxy)- |
CAS | 52364-73-5 |
EINECS | 257-878-5 |
Molecular Formula | C21H25NO |
Molar Mass | 307.43 |
Density | 1.0505 (rough estimate) |
Melting Point | 51-77 °C (lit.) |
Boling Point | 447.93°C (rough estimate) |
Flash Point | >230°F |
Appearance | Morphological liquid crystal (Nematic) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.5614 (estimate) |
MDL | MFCD00075145 |
Use | Application of p-cyanoxybiphenyl can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development process and chemical production process. |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
RTECS | DV1764500 |
TSCA | Yes |
HS Code | 29269090 |
NIST chemical information | Octyloxycyanobiphenyl(52364-73-5) |
EPA chemical information | [1,1'-Biphenyl]-4-carbonitrile, 4'-(octyloxy)- (52364-73-5) |
application | p-cyanooctyloxybiphenyl can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes. |
preparation | 1-bromooctane (20 mmol, 3.5 mL) was added dropwise under nitrogen to the atmosphere of a stirred mixture of 4 '-hydroxy -4-dibenzonitrile (15.4 mmol, 3g) and anhydrous K2CO3 (14.5 mmol, 2g) in 200 mL anhydrous DMSO. Heat the reaction mixture at 110°C for 3 hours. The reaction mixture was added dropwise to 400 mL of 10% NaOH solution at room temperature and filtered. The resulting mixture was vacuum dried and crystallized from ethanol. The product was vacuum dried to obtain p-cyanooctyloxybiphenyl. |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
1-bromooctane (20 mmol, 3.5 mL) was added dropwise under nitrogen to a stirred mixture of 4 '-hydroxy-4-bibenzonitrile (15.4 mmol, 3g) and anhydrous K2CO3 (14.5 mmol, 2g) in 200 mL anhydrous DMSO in the atmosphere. The reaction mixture was heated at 110°C for 3 hours. The reaction mixture was added dropwise to 400 mL of 10% NaOH solution at room temperature and filtered. The resulting mixture was vacuum dried and crystallized from ethanol. The product was vacuum dried to obtain p-cyanooctyloxybiphenyl.