N-Hydroxy-1-(4-methoxyphenyl)methanamine, the chemical formula is C9H13NO2 • HCl, is a white solid powder. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: N-Hydroxy-1-(4-methoxyphenyl)methanamine as a white crystalline solid.
-Melting point: about 150-155°C.
-Solubility: Soluble in water and some organic solvents, such as alcohols and ethers.
Use:
- N-Hydroxy-1-(4-methoxyphenyl)methanamine can be used as an intermediate in organic synthesis for the synthesis of drugs and other compounds.
-It can also be used as a catalyst for some catalytic reactions.
Preparation Method:
N-Hydroxy-1-(4-methoxyphenyl)methanamine can be prepared by reacting p-methoxybenzylamine with sodium nitrite under acidic conditions. Specific steps are as follows:
1. Under acidic conditions such as acetic acid, sodium nitrite is added to the p-methoxybenzylamine solution, and the reaction is stirred.
2. After the reaction is completed, the product is crystallized by cooling to obtain N-Hydroxy-1-(4-methoxyphenyl)methanamine.
Safety Information:
N-Hydroxy-1-(4-methoxyphenyl)methanamine are generally relatively safe under normal conditions of use. However, as a chemical, it still needs to be handled and stored properly. Here are some safety considerations:
-Avoid contact with skin, eyes and respiratory tract: Use chemical protective gloves, goggles and respiratory protective equipment.
-Avoid inhaling dust and avoid ingestion.
-Follow normal laboratory safety operations and comply with relevant regulations and regulations when using and handling.
-Store according to product instructions and avoid contact with incompatible substances.
-Waste disposal should follow local waste management regulations.