2-(4-Bromo-3-methyl-1H-pyrazole-1-yl) acetic acid (also known as (phenyl) acetic acid) is an organic compound. The following are the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White solid
-Molecular formula: C7H8BrN3O2
-relative molecular mass: 238.07g/mol
-Melting point: 223-228 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and methanol
Use:
- 2-(4-bromo-3-methyl-1H-pyrazol-1-yl) acetic acid is commonly used in organic synthesis and can be used as an important intermediate.
-It is also used in the field of medicine, and can be used to synthesize anti-epileptic drugs and anti-cancer drugs.
Preparation Method:
- 2-(4-Bromo-3-methyl-1H-pyrazol-1-yl) acetic acid is usually synthesized by the following steps:
1. Reaction of methyl 1H-pyrazol-1-one with bromoacetic acid to give 2-(3-methyl-1H-pyrazol-1-yl) acetic acid.
2.2-(3-methyl -1H-pyrazol -1-yl) acetic acid reacts with bromine under alkaline conditions to obtain the target product 2-(4-bromo -3-methyl -1H-pyrazol -1-yl) acetic acid.
Safety Information:
- 2-(4-bromo -3-methyl -1H-pyrazol -1-yl) acetic acid is an organic compound, with a certain degree of risk.
-May be irritating to eyes and skin, pay attention to protective measures when in contact.
-Need to operate in a well-ventilated place and wear appropriate protective equipment.
-During storage and handling, follow safe practices and use appropriate containers.