Fmoc-S-3-Amino-3-(3-thienyl)-propionic acid is an organic compound with the following properties: It is a yellow to orange solid with low solubility. Its chemical name is 9-fluorine-based methoxyl, molecular formula is C16H24N2O4S, relative molecular mass is 340.44.
Fmoc-S-3-Amino-3-(3-thienyl)-propionic acid is mainly used for protecting group strategy in peptide synthesis. The Fmoc protecting group is a common amino protecting group that can be removed by photochemical reaction without the use of strong base or acid conditions. Due to the presence of thiophene, Fmoc-S-3-Amino-3-(3-thienyl)-propionic acid also has certain charge transfer properties and can be applied to the material research of organic light-emitting diodes (OLED).
Fmoc-S-3-Amino-3-(3-thienyl)-propionic acid is generally prepared by chemical synthesis. One of the more common methods is the reaction of 3-amino -3-(3-thienyl) propionic acid and Fmoc-OSu, and the esterification reaction occurs under alkali catalysis to obtain Fmoc-S-3-Amino-3-(3-thienyl)-propionic acid.
Regarding safety information, Fmoc-S-3-Amino-3-(3-thienyl)-propionic acid is a chemical agent with certain toxicity. Use should follow the laboratory safety procedures, avoid contact with skin, eyes or inhalation of dust. It is recommended to use in ventilated conditions and wear appropriate protective equipment. If taken by mistake or inhaled by mistake, seek medical attention immediately.