503293-47-8 - Names and Identifiers
503293-47-8 - Physico-chemical Properties
Molecular Formula | C7H4ClFN4
|
Molar Mass | 198.58 |
Density | 1.540±0.06 g/cm3(Predicted) |
Boling Point | 360.1±52.0 °C(Predicted) |
Flash Point | 171.6°C |
Vapor Presure | 2.28E-05mmHg at 25°C |
pKa | 3.20±0.10(Predicted) |
Refractive Index | 1.605 |
503293-47-8 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
503293-47-8 - Introduction
5-(2-chloro-6-fluorophenyl)-2H-tetrazole(5-(2-chloro-6-fluorophenyl)-2H-tetrazole) is an organic compound with the molecular formula C8H4ClFN5 and a molecular weight of 227.6g/mole. It is a white or light yellow crystalline solid, stable at room temperature.
Regarding its properties, 5-(2-chloro-6-fluorophenyl)-2H-tetrazole has low solubility in water, but has high solubility in some organic solvents such as dimethyl sulfoxide and dimethylformamide. It can be characterized and analyzed by nuclear magnetic resonance, mass spectrometry, infrared spectroscopy and other techniques.
5-(2-chloro-6-fluorophenyl)-2H-tetrazole is mainly used in the field of medicine. It is a tetrazolium compound with potential application value in drug research and development. Its derivatives may have antiviral, antitumor and antibacterial activities, and can be used as precursors or intermediates of new drugs. However, it should be pointed out that there are few specific applications of the compound.
Regarding the preparation method, the synthesis method of 5-(2-choro-6-fluorophenyl)-2H-tetrazole is various and can be obtained through different reaction paths. A common synthetic method is to obtain benzoyl cyanamide by the reaction of benzoyl chloride and fluorocyanamide, and then react with indium sulfur chloride to produce indium hexachlorocyanate tetraazide, which is converted to 5-(2-chloroo-6-fluorophenyl)-2H-tetraazole by nucleophilic substitution reaction.
Regarding safety information, due to the lack of specific applications of 5-(2-choro-6-fluorophenyl)-2H-tetrazole, its related toxicology and safety studies are not sufficient. However, in general, chemicals should be handled and used in accordance with laboratory safety procedures and avoid direct contact with skin and eyes. Appropriate protective measures, such as laboratory clothing, gloves and safety goggles, should be used when performing synthesis or operation. It is best to operate in a well-ventilated environment to avoid inhaling dust or splashes. In case of accidental contact or inhalation, rinse the affected area immediately with plenty of water and seek medical help. For safety reasons, please strictly follow the relevant safety guidelines and regulations when using this compound.
Last Update:2024-04-09 21:54:55