500788-90-9 - Names and Identifiers
Name | Boc-R-3-Amino-3-(2,4-dichloro-phenyl)-propionic acid
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Synonyms | BOC-PHG(2,4-CL2)-(C*CH2)OH BOC-D-BETA-PHE(2,4-DICL)-OH Boc-R-3-Amino-3-(2,4-dichloro-phenyl)-propionic acid BOC-(R)-3-AMINO-3-(2,4-DICHLORO-PHENYL)-PROPANOIC ACID BOC-(R)-3-AMINO-3-(2,4-DICHLORO-PHENYL)-PROPIONIC ACID N-BETA-T-BUTOXYCARBONYL-BETA-L-HOMO(2,4-DICHLOROPHENYL)GLYCINE (R)-3-BUTOXYCARBONYL-AMINO-3-(2,4-DICHLORO-PHENYL)PROPIONIC ACID (R)-3-TERT-BUTOXYCARBONYLAMINO-3-(2,4-DICHLORO-PHENYL)-PROPIONIC ACID (Tert-Butoxy)Carbonyl (R)-3-Amino-3-(2,4-dichloro-phenyl)propionic acid
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CAS | 500788-90-9
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500788-90-9 - Physico-chemical Properties
Molecular Formula | C14H17Cl2NO4
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Molar Mass | 334.2 |
Storage Condition | 2-8°C |
500788-90-9 - Introduction
Boc-R-3-Amino-3-(2,4-dichloro-phenyl)-propionic acid is an organic compound containing a Boc protecting group (t-butoxycarbonyl) and a 3-amino -3-(2,4-dichlorophenyl) propionic acid group in its structure.
Nature:
-Appearance: White solid
-Molecular formula: C13H15Cl2NO4
-Molecular weight: 325.17g/mol
-melting point: about 179-181 ℃
Use:
Boc-R-3-amino -3-(2,4-dichlorophenyl) propionic acid is a commonly used organic synthesis intermediates, mainly used in organic synthesis of peptides or protein drugs. It can be used as a protecting group or linking group for amino acids. In addition, it can also be used to synthesize other small molecule compounds with biological activity.
Preparation Method:
Generally, the preparation of Boc-R-3-amino -3-(2,4-dichlorophenyl) propionic acid can be carried out by the following steps:
1. First, it is necessary to synthesize 2,4-dichlorophenylacetic acid. This can be obtained by the reaction of styrene with chloroacetyl chloride, followed by cuprous chloride catalytic reduction.
2. Then, 2,4-dichlorophenylacetic acid is reacted with aminopropionic acid to generate Boc-R-3-amino -3-(2,4-dichlorophenyl) propionic acid. Suitable solvents and catalysts may be used in the reaction.
Safety Information:
Boc-R-3-Amino -3-(2,4-dichlorophenyl) propionic acid has limited safety information and requires careful handling. Laboratory safety procedures should be followed and appropriate personal protective measures should be taken, such as wearing protective glasses, gloves and laboratory coats. When used and stored, it should be kept away from fire and oxidizing agents. Try to avoid contact with the skin and inhalation of its dust or mist.
Last Update:2024-04-09 21:01:54