5-羥色胺
3-(2-aminoethyl)indol-5-ol
CAS: 50-67-9
Molecular Formula: C10H12N2O
5-羥色胺 - Names and Identifiers
| Name | 3-(2-aminoethyl)indol-5-ol |
| Synonyms | Serotonin Serotonine 5-hydroxytryptamine 3-(2-aminoethyl)indol-5-ol 3-(2-AMINOETHYL)INDOL-5-OL 5-Hydroxytryptamine,freebase 3-(2-Aminoethyl)-5-oxyindole 3-(2-aminoethyl)-1H-indol-5-ol 3-(2-azanylethyl)-1H-indol-5-ol 3-(2-AMINOETHYL)-5-HYDROXYINDOLE 3-(2-AMINOETHYL)-5-HYDROXYINDOLE(SEROTONIN) 3-(2-aminoethyl)-1H-indol-5-ol hydrochloride |
| CAS | 50-67-9 |
| EINECS | 200-058-9 |
| InChI | InChI=1/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 |
5-羥色胺 - Physico-chemical Properties
| Molecular Formula | C10H12N2O |
| Molar Mass | 176.22 |
| Density | 1.1102 (rough estimate) |
| Melting Point | 167.5 °C |
| Boling Point | 307.83°C (rough estimate) |
| Flash Point | 205.4°C |
| Solubility | 0.5 g/100 mL (25 °C) |
| Vapor Presure | 1.63E-07mmHg at 25°C |
| Appearance | Solid |
| BRN | 143524 |
| pKa | 9.8(at 25℃) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.7110 (estimate) |
| MDL | MFCD00055054 |
5-羥色胺 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R63 - Possible risk of harm to the unborn child R25 - Toxic if swallowed |
| Safety Description | S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
5-羥色胺 - Reference
| Reference Show more | 1. Huang, he. Effects of 5-hydroxytryptamine and melatonin on improving low temperature tolerance of rapeseed [D]. Chinese Academy of Agricultural Sciences, 2020. 2. Sun, Xiaoshu, et al. "Anti-convulsant effects of cultures." Journal of Ethnopharmacology 262 (2020): 112998.https://doi.org/10.1016/j.jep.2020.11299 3. [IF = 2.952] Chungang Liu et al."Paecilomyces tenuipes extract prevents depression-like behaviors in chronic unpredictable mild stress-induced rat model via modulation of neurotransmitters."Mol Med Rep. 2017 Aug;16(2):2172-2178 4. [IF=7.086] Gaopan Dong et al."Zebrafish neuro-behavioral profiles altered by acesulfame (ACE) within the range of “no observed effect concentrations (NOECs)"."Chemosphere. 2020 Mar;243:125431 5. [IF=4.411] Yueting Cao et al."Chemical Profile and Multicomponent Quantitative Analysis for the Quality Evaluation of Toad Venom from Different Origins."Molecules. 2019 Jan;24(19):3595 6. [IF=3.932] Yiwen Yang et al."Nyctinastic herbs decoction improves para-chlorophenylalanine-induced insomnia by regulating the expression level of neurotransmitters."Ann Transl Med. 2021 Oct; 9(20): 1524 7. [IF=3.69] Xiaoshu Sun et al."Anti-convulsant effects of cultures bear bile powder in febrile seizure via regulation of neurotransmission and inhibition of neuroinflammation."J Ethnopharmacol. 2020 Nov;262:112998 8. [IF=3.512] Yu Sun et al."Integrated Screening of Effective Anti-Insomnia Fractions of Zhi-Zi-Hou-Po Decoction via Drosophila melanogaster and Network Pharmacology Analysis of the Underlying Pharmacodynamic Material and Mechanism."Acs Omega. 2021;6(13):9176-9187 |
5-羥色胺 - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| category | toxic substances |
| toxicity classification | highly toxic |
| acute toxicity | subcutaneous-rat LD50:285 mg/kg; Oral-mouse LD50:60 mg/kg |
| flammability hazard characteristics | combustible; combustion produces toxic nitrogen oxide smoke |
| storage and transportation characteristics | warehouse ventilation and low temperature drying |
| fire extinguishing agent | dry powder, foam, sand, carbon dioxide, mist water |
Last Update：2024-04-09 21:01:54
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View History
5-羥色胺
(3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid
2-Bromo-4-methylpyridine-3-carboxylic acid ethyl ester
N-(4-{[2-(5-isopropenyl-2-methyl-2-cyclohexen-1-ylidene)hydrazino]carbonyl}phenyl)propanamide
2-{[5-(2-ethoxyethyl)-4-hydroxy-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}-N-(4-ethylphenyl)acetamide
SALOR-INT L233331-1EA
对甲苯基异氢酸脂
4-(三丁基锡烷基)-2-甲基噻唑
CYCLOHEXYL-N-VALERATE
Aminophenyltrimethoxysilane
(3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid
2-Bromo-4-methylpyridine-3-carboxylic acid ethyl ester
N-(4-{[2-(5-isopropenyl-2-methyl-2-cyclohexen-1-ylidene)hydrazino]carbonyl}phenyl)propanamide
2-{[5-(2-ethoxyethyl)-4-hydroxy-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}-N-(4-ethylphenyl)acetamide
SALOR-INT L233331-1EA
对甲苯基异氢酸脂
4-(三丁基锡烷基)-2-甲基噻唑
CYCLOHEXYL-N-VALERATE
Aminophenyltrimethoxysilane