5-溴-7-甲酸甲酯-1-Boc-吲哚啉
1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethylethyl) 7-methyl ester
CAS: 860624-87-9
Molecular Formula: C15H18BrNO4
5-溴-7-甲酸甲酯-1-Boc-吲哚啉 - Names and Identifiers
5-溴-7-甲酸甲酯-1-Boc-吲哚啉 - Physico-chemical Properties
| Molecular Formula | C15H18BrNO4 |
| Molar Mass | 356.21 |
5-溴-7-甲酸甲酯-1-Boc-吲哚啉 - Introduction
1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethylethyl) 7-methyl ester(1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethylethyl) is an organic compound. The following describes its nature, use, preparation and safety information:
1. nature:
-chemical formula: C and H and BrNO.
-Molecular weight: 390.246g/mol
-Appearance: White to off-white solid
-Melting point: about 130-132°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and ethanol
-Stability: Stable under dry conditions
2. use:
1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethylethyl) 7-methyl ester is mainly used in the field of organic synthesis and is often used as the starting material or intermediate of various organic compounds. It has high reactivity and can be further converted into compounds with different functional groups through a series of reactions. Because of its indoline structure, the compound also has certain applications in the fields of medicinal chemistry, pesticide chemistry and material science.
3. preparation method:
1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethylethyl) 7-methyl ester can be synthesized by the following steps:
First, indoline is reacted with diazomethane to produce 5-methylindoline. It is then brominated with cuprous bromide to give 5-bromo-7-methylindole. Next, formic acid and an organic solvent are added to the reaction to produce 5-bromo-7-carboxylic acid indole. Finally, the target product 1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethyleyl) 7-methyl ester was obtained by esterification using Boc anhydride and base catalyst.
4. Safety Information:
The safety information about 1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethylethyl) 7-methyl ester is rarely reported. However, since it is an organic bromine compound, attention should be paid to its potential risks to humans and the environment. During use and handling, appropriate protective measures should be taken, including wearing protective gloves, goggles and protective clothing, ensuring adequate ventilation, and following relevant safety procedures. Undertake a comprehensive risk assessment before operation and operate under the guidance of professionals.
1. nature:
-chemical formula: C and H and BrNO.
-Molecular weight: 390.246g/mol
-Appearance: White to off-white solid
-Melting point: about 130-132°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and ethanol
-Stability: Stable under dry conditions
2. use:
1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethylethyl) 7-methyl ester is mainly used in the field of organic synthesis and is often used as the starting material or intermediate of various organic compounds. It has high reactivity and can be further converted into compounds with different functional groups through a series of reactions. Because of its indoline structure, the compound also has certain applications in the fields of medicinal chemistry, pesticide chemistry and material science.
3. preparation method:
1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethylethyl) 7-methyl ester can be synthesized by the following steps:
First, indoline is reacted with diazomethane to produce 5-methylindoline. It is then brominated with cuprous bromide to give 5-bromo-7-methylindole. Next, formic acid and an organic solvent are added to the reaction to produce 5-bromo-7-carboxylic acid indole. Finally, the target product 1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethyleyl) 7-methyl ester was obtained by esterification using Boc anhydride and base catalyst.
4. Safety Information:
The safety information about 1H-Indole-1,7-dicarboxylic acid, 5-bromo-2,3-dihydro-, 1-(1,1-dimethylethyl) 7-methyl ester is rarely reported. However, since it is an organic bromine compound, attention should be paid to its potential risks to humans and the environment. During use and handling, appropriate protective measures should be taken, including wearing protective gloves, goggles and protective clothing, ensuring adequate ventilation, and following relevant safety procedures. Undertake a comprehensive risk assessment before operation and operate under the guidance of professionals.
Last Update：2024-04-09 21:54:55
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