5-溴-2-氟-3-硝基苯甲酸甲酯

5-溴-2-氟-3-硝基苯甲酸甲酯 - Names and Identifiers

Name	Methyl 5-bromo-2-fluoro-3-nitrobenzoate
Synonyms	Methyl 5-bromo-2-fluoro-3-nitrobenzoate Methyl 5-broMo-2-fluoro-3-nitrobenzoate 5-Bromo-2-fluoro-3-nitro-benzoic acid methyl ester Benzoic acid, 5-bromo-2-fluoro-3-nitro-, methyl ester
CAS	1154278-17-7

5-溴-2-氟-3-硝基苯甲酸甲酯 - Physico-chemical Properties

Molecular Formula	C8H5BrFNO4
Molar Mass	278.03
Density	1.742±0.06 g/cm3(Predicted)
Boling Point	345.4±42.0 °C(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Sensitive	IRRITANT
MDL	MFCD12172992

5-溴-2-氟-3-硝基苯甲酸甲酯 - Introduction

Methyl is an organic compound with the chemical formula C8H5BrFNO4. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: 42-44 degrees Celsius
-Boiling point: 300 degrees Celsius
-Relative density: 1.69
-Stability: The compound is unstable under light and should be avoided from exposure to sunlight.

Use:
- Methyl is often used as an intermediate in organic synthesis, especially for the preparation of other organic compounds.
-It can also be used to prepare drugs, pesticides, etc.

Preparation Method:
Methyl can be prepared by the following steps:
1. First, p-nitrobenzene boronic acid reacts with methyl iodide under appropriate reaction conditions to obtain methyl p-nitrobenzene.
2. Then, under alkaline conditions, methyl p-nitrobenzene reacts with tribromomethane to generate methyl 5-bromo-2-methyl-3-nitrobenzoate.
3. Finally, in the presence of a fluorinating reagent, methyl 5-bromo-2-methyl-3-nitrobenzoate is subjected to a fluorination reaction to obtain the target product Metyl.

Safety Information:
-The compound is used and stored in accordance with general laboratory safety procedures.
-It may be irritating to the eyes, skin and respiratory system, so wear appropriate personal protective equipment such as safety glasses, gloves and respiratory protection when handling.
-Avoid inhaling its powder or smoke, and ensure that the operating area is well ventilated.
-If exposed or inhaled, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 21:01:54