5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole - Names and Identifiers
5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole - Physico-chemical Properties
Molecular Formula | C10H6ClF3N2
|
Molar Mass | 246.62 |
Storage Condition | 2-8°C |
Sensitive | IRRITANT |
MDL | MFCD08447542 |
5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole - Introduction
5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole is an organic compound with the molecular formula C10H6ClF3N2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole as a white to pale yellow crystalline solid.
-Melting point: about 124-126 degrees Celsius.
-Solubility: Soluble in organic solvents such as chloroform and dimethyl sulfoxide.
Use:
- 5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole is an important organic synthesis intermediate, which is widely used in drug synthesis and pesticide synthesis. It can be used as a raw material for the synthesis of some pesticides, insecticides and biologically active compounds.
Preparation Method:
- 5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole can be obtained by reacting 2-phenyl -4, 6-dichloropyridine with ammonium trifluoroacetate. The specific steps are as follows: 2-phenyl -4, 6-dichloropyridine reacts with ammonium trifluoroacetate in the presence of a base to generate a quaternary ammonium salt, which is hydrolyzed to give 5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole.
Safety Information:
- 5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole has limited toxicity information, but care should be taken to prevent inhalation, swallowing, and contact with skin. Wear appropriate personal protective equipment, including chemical goggles and protective gloves, when operating. Follow proper laboratory practices when using or handling this compound and dispose of waste properly.
Last Update:2024-04-09 02:00:56