5-BroMo-1H-quinazoline-2,4-dione - Names and Identifiers
Name | 5-Bromoquinazoline-2,4(1H,3H)-dione
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Synonyms | 5-BroMo-1H-quinazoline-2,4-dione 5-Bromoquinazoline-2,4(1H,3H)-dion 5-Bromoquinazoline-2,4(1H,3H)-dione 5-BroMoquinazoline-2,4(1H,3H)-dione 5-Bromo-2,4(1H,3H)-quinazolinedione 2,4(1H,3H)-Quinazolinedione,5-bromo- 5-bromo-1,2,3,4-tetrahydroquinazoline-2,4-dione
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CAS | 959237-01-5
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5-BroMo-1H-quinazoline-2,4-dione - Physico-chemical Properties
Molecular Formula | C8H5BrN2O2
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Molar Mass | 241.04 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
5-BroMo-1H-quinazoline-2,4-dione - Introduction
5-Bromoquinazoline-2,4(1H,3H)-dione is an organic compound with the chemical formula C8H4BrNO2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5-Bromoquinazoline-2,4(1H,3H)-dione is a white to pale yellow solid.
-Melting point: Its melting point is in the range of 224-229 degrees Celsius.
-Solubility: It is soluble in organic solvents such as chloroform and dimethyl sulfoxide, and insoluble in water.
Use:
-Chemical reagent: 5-Bromoquinazoline-2,4(1H,3H)-dione is often used as an intermediate for the synthesis of other organic compounds.
-Drug research: The compound also has certain applications in the field of drug research, for example, it may be used as a precursor or drug fragment of an anti-cancer drug.
Preparation Method:
5-Bromoquinazoline-2,4(1H,3H)-dione has a variety of synthetic methods, the following is one of the common preparation method:
1. First, 3-aminoquinazoline is reacted with bromoalkane to obtain 5-bromoquinazoline.
2.5-Bromoquinazoline-2,4(1H,3H)-dione was obtained by reacting 5-bromoquinazoline-2 with nitric oxide and air oxidation under alkaline conditions.
Safety Information:
There is little public data available on specific safety information about 5-Bromoquinazoline-2,4(1H,3H)-dione. However, as a general rule for handling organic compounds, the following safety measures should be observed when using it:
-Protective measures: Wear appropriate protective gloves, goggles and laboratory coats to ensure a well-ventilated environment.
-operation precautions: avoid direct contact with the skin and inhalation of its dust. Care was taken to avoid ignition and ignition sources under experimental conditions.
-Waste Disposal: Disposal in accordance with local regulations and prescribed chemical waste disposal procedures.
Last Update:2024-04-09 21:54:55