5-(tert-Butyldimethylsilyloxy)-1-pentyne - Names and Identifiers
5-(tert-Butyldimethylsilyloxy)-1-pentyne - Physico-chemical Properties
Molecular Formula | C11H22OSi
|
Molar Mass | 198.38 |
Density | 0.841 g/mL at 25 °C |
Flash Point | 65℃ |
5-(tert-Butyldimethylsilyloxy)-1-pentyne - Risk and Safety
Hazard Symbols | F - Flammable
|
Risk Codes | 10 - Flammable
|
UN IDs | NA 1993 / PGIII |
WGK Germany | 3 |
5-(tert-Butyldimethylsilyloxy)-1-pentyne - Introduction
5-(tert-Butyldimethylsilyloxy)-1-pentyne is an organic compound with the molecular formula C12H26OSi and a molecular weight of 218.42g/mol. It is a colorless liquid with a density of about 0.79g/cm³ at room temperature and a boiling point of about 95-98°C.
5-(tert-Butyldimethylsilyloxy)-1-pentyne is commonly used in the reaction of protecting groups in organic synthesis. It can be obtained by introducing tert-butyldimethylsilylmethylchlorosilane to react with copper bromocyanide, and then continue to react with bromoethane. This compound is often used in synthesis as a reagent to protect hydroxyl or amine groups against attack by other reagents.
The safety of 5-(tert-Butyldimethylsilyloxy)-1-pentyne has not been fully studied, but care should be taken to prevent inhalation, contact with skin and eyes during routine operation. Use should be equipped with appropriate protective equipment, such as gloves, safety glasses and laboratory coats.
In summary, 5-(tert-Butyldimethylsilyloxy)-1-pentyne is a compound used in organic synthesis, mainly used to protect hydroxyl or amine groups. Attention should be paid to safe operation during use.
Last Update:2024-04-10 22:29:15