5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine - Names and Identifiers
Name | 5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine
|
Synonyms | 2-amino-5-p-nitrofenil-1,3,4-tiadiazolo 4-thiadiazole,2-amino-5-(p-nitrophenyl)-3 5-(4-Nitrophenyl)-1,3,4-thiadiazol-2-amine 5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine 2-amino-5-(p-nitrophenyl)-1,3,4-thiadiazole 1,3,4-Thiadiazol-2-aMine, 5-(4-nitrophenyl)- 1,3,4-Thiadiazol-2-amine, 5-(4-nitrophenyl)- 5-(4-nitrophenyl)-1,3,4-thiadiazol-2-ammonium chloride
|
CAS | 833-63-6
|
InChI | InChI=1/C8H6N4O2S/c9-8-11-10-7(15-8)5-1-3-6(4-2-5)12(13)14/h1-4H,(H2,9,11) |
5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine - Physico-chemical Properties
Molecular Formula | C8H6N4O2S
|
Molar Mass | 222.22 |
Density | 1.535g/cm3 |
Melting Point | 257-261 °C (lit.) |
Boling Point | 454.4°C at 760 mmHg |
Flash Point | 228.6°C |
Vapor Presure | 1.91E-08mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.703 |
5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
RTECS | XI3603000 |
5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine - Introduction
5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine is an organic compound with the chemical formula C8H6N6O2S. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine is a solid substance, generally yellow to orange crystals.
-Solubility: It is soluble in many organic solvents, such as ethanol, xylene, etc., but its solubility in water is low.
-Melting point: Its melting point is between 170-175°C.
Use:
5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine can be used as an intermediate or raw material in the synthesis of drugs and pesticides. It can also be used as a raw material for dyes and pigments.
Preparation Method:
A common preparation method is to obtain 5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine by reacting p-nitrophenylacetic acid with thiourea. First, thiourea and sodium hydroxide are reacted in a suitable solvent to form sodium bisulfate. The p-nitrophenylacetic acid is then reacted with sodium bisulfate to give the corresponding substituted product. Finally, the product is subjected to reduction and crystallization steps to obtain the target compound.
Safety Information:
- 5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine is an organic compound, which should be used to prevent the risk of fire and explosion.
-During operation, you need to wear appropriate personal protective equipment, such as laboratory gloves, glasses and laboratory clothing, to avoid skin contact and eye irritation.
-There are no other clear toxicity data for this compound, but the general operating specifications of hazardous chemicals in the laboratory should be followed, and the experimental environment and operating risks should be strictly controlled.
Note: The above information is for reference only. For specific preparation methods and safety precautions, please refer to relevant literature and laboratory guidelines.
Last Update:2024-04-09 21:01:54