5-(4-Bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine - Names and Identifiers
5-(4-Bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine - Physico-chemical Properties
Molecular Formula | C9H9BrN2O
|
Molar Mass | 241.08 |
Storage Condition | Room Temprature |
Sensitive | IRRITANT |
MDL | MFCD18651788 |
5-(4-Bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine - Risk and Safety
5-(4-Bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine - Introduction
5-(4-Bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine is an organic compound also known as 2-amino-4, 5-dihydro-1, 3-oxazol-2-one. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
-Appearance: colorless to light yellow crystal
-Molecular formula: C10H10BrN3O
-Molecular weight: 267.11g/mol
-melting point: 120-122 ℃
-Soluble: Soluble in ether, dimethyl ketone and chloroform, practically insoluble in water
Use:
- 5-(4-Bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine can be used as a drug intermediate and has potential application value in drug research and development.
-It can also be used in organic synthesis reactions, such as when constructing complex organic molecules and synthesizing new compounds.
Preparation Method:
The synthesis of -5-(4-Bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine is usually carried out by ring opening reaction and amination reaction.
-In the general synthesis method, 4-bromoacetophenone is first synthesized by the reaction of chlorinated hydrocarbon and propionamide. It is then reacted with a cyclization reagent (e. g., sodium cyanate and an alcohol) to form 4-(4-bromophenyl)-4,5-dihydro-l, 3-oxazol-2-one. Finally, reaction with an amine (e. g., aqueous ammonia) gives 5-(4-Bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine.
Safety Information:
- 5-(4-Bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine is generally safe under correct operation.
-When using, care should be taken to avoid contact with skin, eyes and respiratory tract.
-When performing laboratory work, appropriate personal protective measures should be taken, such as wearing chemical protective gloves and goggles.
-If contact or aspiration occurs, rinse immediately with plenty of water and seek medical help.
Please note that the preparation and use of this compound must comply with laboratory safety procedures and follow relevant laws and regulations.
Last Update:2024-04-09 21:00:56