5,6-Difluorindolin - Names and Identifiers
Name | 5,6-difluoroindoline
|
Synonyms | 5,6-Difluorindolin 5,6-difluoroindoline 5,6-Difluoroindoline 5,6-difluoro-2,3-dihydro-1H-indole 1H-Indole, 5,6-difluoro-2,3-dihydro- 1H-indole, 5,6-difluoro-2,3-dihydro-
|
CAS | 954255-04-0
|
InChI | InChI=1/C8H7F2N/c9-6-3-5-1-2-11-8(5)4-7(6)10/h3-4,11H,1-2H2 |
5,6-Difluorindolin - Physico-chemical Properties
Molecular Formula | C8H7F2N
|
Molar Mass | 155.14 |
Density | 1.261±0.06 g/cm3(Predicted) |
Boling Point | 207.0±40.0 °C(Predicted) |
Flash Point | 79°C |
Vapor Presure | 0.23mmHg at 25°C |
pKa | 4.30±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.516 |
5,6-Difluorindolin - Introduction
5,6-difluoroindoline(5,6-difluoroindoline) is a fluorine-containing organic compound. Its chemical formula is C8H5F2N and its molecular weight is 150.13g/mol. The following is a description of the nature, use, formulation and safety information of 5,6-difluoroindoline:
Nature:
-Appearance: 5,6-difluoroindoline is a colorless or light yellow solid.
-Melting point: about 90-95 ℃.
-Boiling point: approximately 280°C.
-Soluble: It is soluble in common organic solvents, such as methanol, chloroform and dichloromethane.
Use:
- 5,6-difluoroindoline is an intermediate used to prepare other compounds, which can be further modified into organic compounds with various properties through a variety of chemical reactions.
-It is widely used in pharmaceutical research and organic synthesis, and can be used as a reaction starter or catalyst.
Preparation Method:
There are several preparation methods of 5,6-difluoroindoline, and a common method is obtained by the amination reaction of 5,6-difluoroindole. A specific procedure involves reacting the 5,6-difluoroindole with an amination agent such as p-methoxybenzylamine in a suitable solvent, usually at elevated temperature and pressure.
Safety Information:
-The use of 5,6-difluoroindoline should follow laboratory safety practices.
-It is an organic compound that may have potentially toxic and irritating effects on the human body.
-When handling or operating 5,6-difluoroindoline, you should wear appropriate protective gloves and eye protection, and operate in a well-ventilated place.
-When storing 5,6-difluoroindoline, the container should be sealed and stored in a dry, cool place, away from fire and oxidizing agents.
Please note that this information is for reference only, and the specific use and operation requirements should be carried out according to the actual situation and laboratory regulations.
Last Update:2024-04-09 15:18:00