5,5-Dimethyl-2-(pyridin-3-yl)-1,3,2-dioxaborinane

5,5-Dimethyl-2-(pyridin-3-yl)-1,3,2-dioxaborinane - Names and Identifiers

Name	3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine
Synonyms	PYRIDINE-3-BORONIC ACID, NEOPENTYL ESTER 2-(3-PYRIDYL)-5,5-DIMETHYL-1,2,3-DIOXABORANE PYRIDINE-3-BORONIC ACID NEOPENTYLGLYCOL ESTER 2-(3-PYRIDIL)-5,5-DIMETHYL-1,3,2-DIOXABORONANE 2-(4-PYRIDYL)-5,5-DIMETHYL-1,2,3-DIOXABORINANE 2-(3-PYRIDYL)-5,5-DIMETHYL-1,3,2-DIOXABORINANE 3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine 5,5-Dimethyl-2-(pyridin-3-yl)-1,3,2-dioxaborinane 5,5-Dimethyl-2-(3-pyridyl)-1,3,2-dioxaborinane, Pyridine-3-boronic acid neopentylglycol ester
CAS	845885-86-1
InChI	InChI=1/C10H14BNO2/c1-10(2)7-13-11(14-8-10)9-3-5-12-6-4-9/h3-6H,7-8H2,1-2H3

5,5-Dimethyl-2-(pyridin-3-yl)-1,3,2-dioxaborinane - Physico-chemical Properties

Molecular Formula	C10H14BNO2
Molar Mass	191.03
Density	1.05±0.1 g/cm3(Predicted)
Melting Point	92-96 °C (lit.)
Boling Point	309.8±15.0 °C(Predicted)
Flash Point	141.2°C
Vapor Presure	0.00114mmHg at 25°C
pKa	5.22±0.12(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.491

5,5-Dimethyl-2-(pyridin-3-yl)-1,3,2-dioxaborinane - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
Hazard Class	IRRITANT

5,5-Dimethyl-2-(pyridin-3-yl)-1,3,2-dioxaborinane - Introduction

3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine is an organic compound with the chemical formula C12H17BNO3. The following is a brief description of its nature, use, formulation and safety information:

Nature:
3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine is a colorless to pale yellow solid. It has a melting point of about 65-67°C and a density of 1.1g/cm³. It is organic solvent soluble at normal temperature.

Use:
3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine are mainly used in the field of organic synthesis. It is a boron-containing reagent that can be used in Suzuki-Miyaura coupling reactions to perform carbon-carbon bond formation, which helps to construct organic molecular frameworks. In addition, it can also be used for other cross-coupling reactions, selective oxidation reactions and catalytic reactions.

Preparation Method:
3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine are generally prepared by chemical synthesis. One common method is to react the corresponding pyridine boronic ester and neopentyl glycol ester with base catalysis to produce the desired product. The specific reaction conditions and procedures can be adjusted according to the needs of the laboratory.

Safety Information:
When using 3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine, please follow the safety regulations for general chemical laboratory operations. Avoid direct contact with skin and eyes, and make sure to operate in a well-ventilated area. Seek prompt medical help in case of accidental contact or inhalation. In addition, it needs to be stored at room temperature and away from fire and oxidizing agents.

Last Update：2024-04-10 22:29:15