Molecular Formula | C16H12O5 |
Molar Mass | 284.26 |
Density | 1.448±0.06 g/cm3 (20 ºC 760 Torr) |
Melting Point | 242-243℃ |
Boling Point | 528.0±50.0 °C(Predicted) |
Solubility | Soluble in DMSO, methanol and other solutions. |
Appearance | Yellow powder |
pKa | 6.60±0.20(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD18452296 |
Physical and Chemical Properties | Orange-yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from cassia seed. |
In vitro study | Obtusifolin (1, 10, 100 μM) inhibits MUC5AC gene expression induced by EGF, PMA, or TNF-α in NCI-H292 cells. |
Reference Show more | 1. Xie, Li, et al. "Development of an UHPLC-MS/MS method for comparative pharmacokinetics of nine anthraquinones in rats and application to dosage conversion between different Semen Cassiae forms." Journal of pharmaceutical and biomedical analysis 174 (2019): 2. [IF=3.935] Li Xie et al."Development of an UHPLC-MS/MS method for comparative pharmacokinetics of nine anthraquinones in rats and application to dosage conversion between different Semen Cassiae forms."J Pharmaceut Biomed. 2019 Sep;174:696 |