Name | (4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)Methanone |
Synonyms | SMI481 (4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)Methanone |
CAS | 432020-20-7 |
Molecular Formula | C17H15ClFN3O3 |
Molar Mass | 363.7707032 |
Solubility | Soluble in DMSO |
Storage Condition | 2-8°C |
Use | SMI481 is the first small-molecule inhibitor of Sec14-like phosphatidylinositol transfer proteins (PITPs). |
Reference Show more | 1: Nile AH, Tripathi A, Yuan P, Mousley CJ, Suresh S, Wallace IM, Shah SD, Pohlhaus DT, Temple B, Nislow C, Giaever G, Tropsha A, Davis RW, St Onge RP, Bankaitis VA. PITPs as targets for selectively interfering with phosphoinositide signaling in cells. Nat Chem Biol. 2014 Jan;10(1):76-84. doi: 10.1038/nchembio.1389. Epub 2013 Nov 24. PubMed PMID: 24292071; PubMed Central PMCID: PMC4059020. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.749 ml | 13.745 ml | 27.49 ml |
5 mM | 0.55 ml | 2.749 ml | 5.498 ml |
10 mM | 0.275 ml | 1.374 ml | 2.749 ml |
5 mM | 0.055 ml | 0.275 ml | 0.55 ml |