Name: AVIPTADIL
CAS: 40077-57-4
Molecular Formula: C147H237N43O43S
Molecular Weight: 3326.78
40077-57-4 - Names and Identifiers
| Name | AVIPTADIL |
| Synonyms | Aviptadil Acetate |
| CAS | 40077-57-4 |
| InChI | InChI=1/C147H237N43O43S/c1-18-75(12)115(142(229)180-96(56-72(6)7)131(218)183-104(145(232)233)63-110(155)200)188-139(226)106(68-192)185-134(221)101(62-109(154)199)177-130(217)95(55-71(4)5)174-132(219)97(58-81-37-41-84(195)42-38-81)175-125(212)88(33-23-26-49-149)167-123(210)89(34-24-27-50-150)171-140(227)113(73(8)9)186-118(205)76(13)164-121(208)93(47-53-234-17)170-127(214)92(45-46-107(152)197)169-122(209)87(32-22-25-48-148)166-124(211)90(35-28-51-161-146(156)157)168-129(216)94(54-70(2)3)173-126(213)91(36-29-52-162-147(158)159)172-143(230)116(78(15)193)189-136(223)98(59-82-39-43-85(196)44-40-82)176-133(220)100(61-108(153)198)178-135(222)103(65-112(203)204)182-144(231)117(79(16)194)190-137(224)99(57-80-30-20-19-21-31-80)181-141(228)114(74(10)11)187-119(206)77(14)165-128(215)102(64-111(201)202)179-138(225)105(67-191)184-120(207)86(151)60-83-66-160-69-163-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,191-196H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,197)(H2,153,198)(H2,154,199)(H2,155,200)(H,160,163)(H,164,208)(H,165,215)(H,166,211)(H,167,210)(H,168,216)(H,169,209)(H,170,214)(H,171,227)(H,172,230)(H,173,213)(H,174,219)(H,175,212)(H,176,220)(H,177,217)(H,178,222)(H,179,225)(H,180,229)(H,181,228)(H,182,231)(H,183,218)(H,184,207)(H,185,221)(H,186,205)(H,187,206)(H,188,226)(H,189,223)(H,190,224)(H,201,202)(H,203,204)(H,232,233)(H4,156,157,161)(H4,158,159,162)/t75-,76-,77-,78+,79+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,113-,114-,115-,116-,117-/m0/s1 |
40077-57-4 - Physico-chemical Properties
| Molecular Formula | C147H237N43O43S |
| Molar Mass | 3326.78 |
40077-57-4 - Nature
- This product is twenty-eight peptide, belonging to the Secretin family. The structure is similar to that of incretin and glucagon. It is widely distributed in the body, and VIP is distributed in most systems and organs, even in neutrophils and mast cells. VIP immunoreactive is present throughout the gastrointestinal tract from the salivary glands of the oral cavity to the rectum. The highest content in the duodenum, followed by the ileum. Its basic concentration in the circulating blood is very low, half-life (0. 85±0.12) min, liver, kidney, brain are cleared it.
- the effect of VIP on the digestive system is to inhibit the contraction of lower esophageal sphincter, stomach, small intestinal circular muscle, gallbladder and anal sphincter of large intestine; Promote the secretion of water and electrolyte in intestinal mucosa; stimulate the secretion of water and electrolytes in the external part of the pancreas, bile and small intestine; Inhibit gastric secretion of gastric acid, water and electrolytes; Stimulate gastrointestinal endocrine cells to secrete insulin, glucagon, somatostatin and pancreatic polypeptide, excitatory enteric neurons. On the circulation and respiratory system, VIP has a moderate positive inotropic effect on the myocardium, increasing cardiac output; Has a diastolic effect on most vascular beds, can reduce diastolic blood pressure and mean arterial pressure, dilates the smooth muscles of the trachea and bronchi and increases ventilation; The effect on neuroendocrine is to stimulate the pituitary to release prolactin, growth hormone, ACTH and LH, and to stimulate the release of renin from the Pararenal cells.
Last Update：2022-01-01 11:11:48
40077-57-4 - Use
The determination of plasma VIP concentration can be used as a diagnostic measure of VIP tumor, and can also be used as an indicator of treatment or tumor proliferation.
Last Update：2022-01-01 11:11:48
AVIPTADIL suppliers
Product Name： Aviptadil, Vasoactive Intestinal Peptide, VIP
CAS ： 40077-57-4
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CAS ： 40077-57-4
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Product Name： Aviptadil Acetate
CAS ： 40077-57-4
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CAS ： 40077-57-4
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