ACID ETHYL ESTER is a chemical compound also known as 1,2-dihydro-4-hydroxy-2-keto-3-quinolinecarboxylic ACID ETHYL ESTER. The following is a description of the properties, uses, preparation methods and safety information of the compound:
Nature:
-Appearance: 1, ACID ETHYL ESTER is yellow crystal or powder.
-Molecular formula: C11H9NO4
-Molecular weight: 223.19g/mol
-Melting Point: about 110-112 ° C
-Boiling point: About 370 ° C
Use:
- 1, acethyl ESTER is a drug intermediate commonly used in the synthesis of antibiotics, antiviral drugs and anti-cancer drugs and other drug compounds.
-It can also be used as a photosensitizer, dye and raw material for organic synthesis.
Method:
1. The preparation of ACID ETHYL ESTER can be carried out by the following steps:
1. The amino ketone reacts with formic acid and sulfuric acid to generate 2-hydroxyquinoline -3-carboxylic acid.
2. In anhydrous ether, it reacts with acid chloride to generate 2,4-dihydroxyquinoline -3-carboxylic acid ethyl acetate.
3. Finally, the product is reacted with ethanol to obtain 1, ACID ETHYL ESTER.
Safety Information:
- 1, ACID ETHYL ESTER has certain toxicity and needs to be handled carefully.
-Avoid contact with oxidants, strong bases and strong acids during use or storage.
-Use with suitable protective gloves, glasses and a protective mask to avoid direct contact with skin, eyes and respiratory tract. During operation, good ventilation should be maintained.
-Safety practices should be followed when handling and storing the substance. If you are accidentally poisoned or exposed, you should seek medical attention immediately.