4-羟基-2-硫代-6-(二氟甲基)嘧啶 - Names and Identifiers
4-羟基-2-硫代-6-(二氟甲基)嘧啶 - Physico-chemical Properties
Molecular Formula | C5H4F2N2OS
|
Molar Mass | 178.16 |
Density | 1.54±0.1 g/cm3(Predicted) |
pKa | 6.62±0.20(Predicted) |
Storage Condition | Room Temprature |
4-羟基-2-硫代-6-(二氟甲基)嘧啶 - Introduction
4-Hydroxy-6-(difluoromethyl) pyrimidine-2-thiol is a sulfur-containing organic compound with the chemical formula C6H3F2N3OS.
Nature:
1. Appearance: white crystalline powder.
2. Solubility: Soluble in water and many organic solvents.
3. melting point: about 170-174 degrees Celsius.
Use:
4-Hydroxy-6-(difluoromethyl) pyrimidine-2-thiol is a multifunctional compound commonly used in the field of organic synthesis. Specific applications include:
1. pharmaceutical field: as a drug intermediate, used in the synthesis of biologically active compounds.
2. pesticide field: used as pesticide intermediates, used in the synthesis of pesticides.
Preparation Method:
The preparation method of 4-hydroxy-6-(difluoromethyl) pyrimidine-2-thiol can be carried out by the following steps:
1.2,4-difluoromethyl pyrimidine reacts with thiol to generate 2,4-difluoromethyl -6-thiol pyrimidine.
2. Oxidation of 2,4-difluoromethyl-6-thiolpyrimidine to obtain 4-hydroxy-6-(difluoromethyl) pyrimidine -2-thiol.
Safety Information:
When using and handling 4-hydroxy-6-(difluoromethyl) pyrimidine-2-thiol, the following safety precautions should be paid attention:
1. avoid contact with skin, eyes, so as not to cause irritation and damage.
2. avoid inhaling its dust or steam, it is recommended to operate in a well-ventilated place.
3. storage should avoid high temperature and fire.
4. transport should pay attention to prevent collision and leakage.
5. carefully read and understand the relevant safety technical instructions before use.
Last Update:2024-04-09 15:17:51