Name | 2-Amino-4-chloropyridine |
Synonyms | IFLAB-BB F1926-0004 4-chloro-2-pyridinamine 4-CHLOROPYRIDIN-2-AMINE 4-chloropyridin-2-amine 2-AMINO-4-CHLOROPYRIDINE 2-Amino-4-chloropyridine 4-Chloro-2-amine-pyridin 4-Chloro-2-aminopyridine 2-Amino-4-Chloro Pyridine 4-CHLORO-2-PYRIDINYLAMINE 2-amino-4-chloropyridinium 4-CHLORO-PYRIDIN-2-YLAMINE 4-Chloro-pyridin-2-ylamine 4-CHLORO-PYRIDINE-2-YLAMINE |
CAS | 19798-80-2 |
EINECS | 629-610-0 |
InChI | InChI=1/C5H5ClN2/c6-4-1-2-8-5(7)3-4/h1-3H,(H2,7,8)/p+1 |
Molecular Formula | C5H5ClN2 |
Molar Mass | 128.56 |
Density | 1.326±0.06 g/cm3(Predicted) |
Melting Point | 126-127°C |
Boling Point | 240.8±20.0 °C(Predicted) |
Flash Point | 99.4°C |
Solubility | DMSO, Methanol |
Vapor Presure | 0.0372mmHg at 25°C |
Appearance | Bright yellow crystal |
Color | Colorless to yellow to brown |
Maximum wavelength(λmax) | ['294nm(CHCl3)(lit.)'] |
pKa | 5.72±0.11(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Sensitive | Air & Moisture Sensitive |
MDL | MFCD04113820 |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
HS Code | 29333990 |
Hazard Class | IRRITANT |
Introduction | 2-amino-4-chloropyridine is a white solid, which can be prepared from 2-pyridine carboxylic acid as raw material 4-chloropyridine-2-amide, and then react with calcium hypochlorite to obtain 2-amino-4-chloropyridine. |
Application | 2-amino-4-chloro-pyridine can be used to prepare 4-fluoro-2-aminopyridine, 4-fluoro-2-aminopyridine It is an important intermediate for preparing tyrosine kinase inhibitors, P13K inhibitors, aldosterone synthase inhibitors and other inhibitors, and has broad application prospects. |