4-氨基-5-甲氧基嘧啶
4-Amino-5-methoxypyrimidine
CAS: 695-86-3
Molecular Formula: C5H7N3O
4-氨基-5-甲氧基嘧啶 - Names and Identifiers
| Name | 4-Amino-5-methoxypyrimidine |
| Synonyms | 5-methoxypyrimidin-4-amine 4-amino-5-methoxypyrimdine 5-Methoxy-4-pyrimidinamine 5-MethoxypyriMidin-4-aMine 4-Amino-5-methoxypyrimidine 4-Pyrimidinamine, 5-methoxy- 4-Pyrimidinamine, 5-Methoxy- 4-Pyrimidinamine, 5-methoxy- (9CI) |
| CAS | 695-86-3 |
| InChI | InChI=1/C5H7N3O/c1-9-4-2-7-3-8-5(4)6/h2-3H,1H3,(H2,6,7,8) |
4-氨基-5-甲氧基嘧啶 - Physico-chemical Properties
| Molecular Formula | C5H7N3O |
| Molar Mass | 125.13 |
| Density | 1.224±0.06 g/cm3(Predicted) |
| Melting Point | 118.5-119.0 °C |
| Boling Point | 264.3±20.0 °C(Predicted) |
| Flash Point | 113.6°C |
| Vapor Presure | 0.00981mmHg at 25°C |
| pKa | 5.04±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.566 |
4-氨基-5-甲氧基嘧啶 - Introduction
4-Amino-5-methoxypyrimidine(4-Amino-5-methoxypyrimidine) is an organic compound with the molecular formula C5H7N3O and a molecular weight of 125.13g/mole. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 4-Amino-5-methoxypyrimidine exists in the form of white crystals.
2. Solubility: It is soluble in water, alcohol and ether.
Use:
1. Drug synthesis: 4-Amino-5-methoxypyrimidine is an important intermediate for the synthesis of various drugs, such as anti-tumor drugs.
2. Pesticide synthesis: It is also used to synthesize certain pesticides, such as herbicides and insecticides.
Preparation Method:
4-Amino-5-methoxypyrimidine has many preparation methods, the following is one of them:
Step 1: Add pyrimidine to methyl chloride, and add methyl alcohol and hydrochloric acid catalyst.
Step 2: Aqueous ammonia was slowly added dropwise to the reaction solution.
Step 3: Stir at room temperature to allow the reaction to continue.
Step 4: The reaction solution was separated by filtration and then washed with hydrochloric acid.
Step 5: The product was purified by vacuum distillation or crystallization.
Safety Information:
1. 4-Amino-5-methoxypyrimidine needs to be operated in a well-ventilated place to avoid inhaling its dust or vapor.
2. It is irritating to eyes and skin, and contact with skin and eyes should be avoided.
3. use should wear protective gloves and goggles and other personal protective equipment.
4. Keep sealed during storage and handling to avoid contact with oxidants and strong acids.
Nature:
1. Appearance: 4-Amino-5-methoxypyrimidine exists in the form of white crystals.
2. Solubility: It is soluble in water, alcohol and ether.
Use:
1. Drug synthesis: 4-Amino-5-methoxypyrimidine is an important intermediate for the synthesis of various drugs, such as anti-tumor drugs.
2. Pesticide synthesis: It is also used to synthesize certain pesticides, such as herbicides and insecticides.
Preparation Method:
4-Amino-5-methoxypyrimidine has many preparation methods, the following is one of them:
Step 1: Add pyrimidine to methyl chloride, and add methyl alcohol and hydrochloric acid catalyst.
Step 2: Aqueous ammonia was slowly added dropwise to the reaction solution.
Step 3: Stir at room temperature to allow the reaction to continue.
Step 4: The reaction solution was separated by filtration and then washed with hydrochloric acid.
Step 5: The product was purified by vacuum distillation or crystallization.
Safety Information:
1. 4-Amino-5-methoxypyrimidine needs to be operated in a well-ventilated place to avoid inhaling its dust or vapor.
2. It is irritating to eyes and skin, and contact with skin and eyes should be avoided.
3. use should wear protective gloves and goggles and other personal protective equipment.
4. Keep sealed during storage and handling to avoid contact with oxidants and strong acids.
Last Update：2024-04-09 02:00:47
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Spot supply
Product Name: 5-Methoxypyrimidin-4-amine Visit Supplier Webpage Request for quotationCAS: 695-86-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 5-Methoxypyrimidin-4-amine Visit Supplier Webpage Request for quotationCAS: 695-86-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
4-氨基-5-甲氧基嘧啶
六氢-1-甲基-4H-氮杂革-4-酮 N-甲基高哌啶酮
(3S)-3-氨基-4-苯基丁酸叔丁酯
2-(((6-(4-(2-羟乙基)哌嗪-1-基)-2-甲基嘧啶-4-基)氨基)-N-(邻甲苯基)噻唑-5-羧酰胺
Ethanone, 1-tetracyclo[3.2.0.02,7.04,6]hept-1-yl- (9CI)
1-[2-[(2R)-4-[2-[3,5-双(三氟甲基)苯基]乙酰基]-2-(3,4-二氯苯基)-2-吗啉基]乙基]-ALPHA,ALPHA-二甲基-4-哌啶乙酰胺
(6-氯-3-氧代-2,3-二氢哒嗪-4-基)氨基甲酸叔丁酯
PALM KERNELAMIDE DEA
Lithium Acetate
1-CBZ-AMINO-3-CYCLOPROPANECARBONYL-BENZENE
六氢-1-甲基-4H-氮杂革-4-酮 N-甲基高哌啶酮
(3S)-3-氨基-4-苯基丁酸叔丁酯
2-(((6-(4-(2-羟乙基)哌嗪-1-基)-2-甲基嘧啶-4-基)氨基)-N-(邻甲苯基)噻唑-5-羧酰胺
Ethanone, 1-tetracyclo[3.2.0.02,7.04,6]hept-1-yl- (9CI)
1-[2-[(2R)-4-[2-[3,5-双(三氟甲基)苯基]乙酰基]-2-(3,4-二氯苯基)-2-吗啉基]乙基]-ALPHA,ALPHA-二甲基-4-哌啶乙酰胺
(6-氯-3-氧代-2,3-二氢哒嗪-4-基)氨基甲酸叔丁酯
PALM KERNELAMIDE DEA
Lithium Acetate
1-CBZ-AMINO-3-CYCLOPROPANECARBONYL-BENZENE