4-氨基-2-氯-5-嘧啶羧酸乙酯

4-氨基-2-氯-5-嘧啶羧酸乙酯 - Names and Identifiers

Name	Ethyl 4-amino-2-chloropyrimidine-5-carboxylate
Synonyms	127838 Ethyl 4-amino-2-chloro-5-pyrimidinecarboxylate Ethyl 4-amino-2-chloropyrimidine-5-carboxylate 5-PyriMidinecarboxylicacid,4-aMino-2-chloro-,ethyleste 4-AMino-2-chloropyriMidine-5-carboxylicacid ethyl ester 4-amino-2-chloro-5-pyrimidinecarboxylic acid ethyl ester 5-Pyrimidinecarboxylic acid,4-amino-2-chloro-,ethyl ester
CAS	71406-78-5
EINECS	200-258-5

4-氨基-2-氯-5-嘧啶羧酸乙酯 - Physico-chemical Properties

Molecular Formula	C7H8ClN3O2
Molar Mass	201.61
Density	1.395
Melting Point	156℃
Boling Point	377℃
Flash Point	182℃
pKa	0.55±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive	Irritant
MDL	MFCD09860847

4-氨基-2-氯-5-嘧啶羧酸乙酯 - Introduction

Ethyl, chemical formula for C8H8ClN3O2, is an organic compound.

Nature:
-Appearance: Colorless crystalline solid
-Melting point: about 132-134 degrees Celsius
-Solubility: Soluble in many organic solvents such as chloroform, dimethyl ketone and methanol

Use:
- Ethyl is an important intermediate compound that can be used to synthesize biologically active compounds and drugs.
-It can be used to synthesize anticancer drugs, anti-tuberculosis drugs, etc.

Preparation Method:
Ethyl can be prepared by the following steps:
1. Dissolve ethyl chloroformate in dimethyl ketone.
2. Add ammonia and react at low temperature.
3. Add 2-chloropyrimidine and continue the reaction at an appropriate temperature.
4. The product was filtered, crystallized, and then purified.

Safety Information:
- Ethyl is generally stable and safe under normal use and storage conditions.
-But as a chemical substance, it may have certain toxicity and irritation to the human body.
-During use, you must follow the safe operation procedures of the chemical laboratory, wear protective gloves and glasses, and ensure that you operate in a well-ventilated area.
-If you have unintended contact with skin or eyes, rinse immediately with water and seek medical help.

Last Update：2024-04-09 15:18:08