4-乙基-3-溴吡啶
3-Bromo-4-ethyl-pyridine
CAS: 38749-76-7
Molecular Formula: C7H8BrN
4-乙基-3-溴吡啶 - Names and Identifiers
| Name | 3-Bromo-4-ethyl-pyridine |
| Synonyms | 4-Ethyl-3-Bromopyridine 4-Ethyl-3-bromopyridine 3-Bromo-4-ethyl-pyridine Pyridine, 3-bromo-4-ethyl- Pyridine, 3-bromo-4-ethyl- (9CI) |
| CAS | 38749-76-7 |
| InChI | InChI=1/C7H8BrN/c1-2-6-3-4-9-5-7(6)8/h3-5H,2H2,1H3 |
4-乙基-3-溴吡啶 - Physico-chemical Properties
| Molecular Formula | C7H8BrN |
| Molar Mass | 186.05 |
| Density | 1.413±0.06 g/cm3(Predicted) |
| Boling Point | 216.7±20.0 °C(Predicted) |
| Flash Point | 84.8°C |
| Vapor Presure | 0.203mmHg at 25°C |
| pKa | 3.68±0.18(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.544 |
4-乙基-3-溴吡啶 - Introduction
3-Bromo-4-ethyl-pyridine is an organic compound with the chemical formula C8H10BrN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless liquid or solid.
-Molecular weight: 207.08g/mol.
-Melting point:-17°C.
-Boiling point: 206-208°C.
-Density: 1.444g/cm³.
-Solubility: Soluble in organic solvents, slightly soluble in water.
Use:
- 3-Bromo-4-ethyl-pyridine is commonly used as an intermediate in organic synthesis.
-It can be used to prepare optically active molecules and pharmaceutical compounds.
-The compound can also be used as a catalyst, a complexing agent and a halogenating agent.
Preparation Method:
The preparation method of 3-Bromo-4-ethyl-pyridine can be carried out by the following steps:
1. 3-bromopyridine is reacted with vinyl magnesium halide (such as ethyl magnesium bromide) in an inert solvent (such as dimethylformamide).
2. The reaction mixture was cooled and acidified to give the desired product.
Safety Information:
-3-Bromo-4-ethyle-pyridine is a flammable liquid, need to pay attention to fire prevention measures.
-When using or operating, it is recommended to wear protective glasses and gloves to avoid contact with skin and eyes.
-The compound may be harmful to the environment, and care should be taken to prevent it from entering water or soil.
-Appropriate safety practices should be followed during storage and handling. Observe local laws and regulations during waste disposal.
Nature:
-Appearance: Colorless liquid or solid.
-Molecular weight: 207.08g/mol.
-Melting point:-17°C.
-Boiling point: 206-208°C.
-Density: 1.444g/cm³.
-Solubility: Soluble in organic solvents, slightly soluble in water.
Use:
- 3-Bromo-4-ethyl-pyridine is commonly used as an intermediate in organic synthesis.
-It can be used to prepare optically active molecules and pharmaceutical compounds.
-The compound can also be used as a catalyst, a complexing agent and a halogenating agent.
Preparation Method:
The preparation method of 3-Bromo-4-ethyl-pyridine can be carried out by the following steps:
1. 3-bromopyridine is reacted with vinyl magnesium halide (such as ethyl magnesium bromide) in an inert solvent (such as dimethylformamide).
2. The reaction mixture was cooled and acidified to give the desired product.
Safety Information:
-3-Bromo-4-ethyle-pyridine is a flammable liquid, need to pay attention to fire prevention measures.
-When using or operating, it is recommended to wear protective glasses and gloves to avoid contact with skin and eyes.
-The compound may be harmful to the environment, and care should be taken to prevent it from entering water or soil.
-Appropriate safety practices should be followed during storage and handling. Observe local laws and regulations during waste disposal.
Last Update：2024-04-09 15:17:57
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View History
4-乙基-3-溴吡啶
N-{2-[2-(sec-Butyl)phenoxy]ethyl}-2-isopropylaniline
2-(氨甲基)-1H苯并[d]咪唑-6-羧酸盐酸盐
1-(6-乙氧基-2-甲硫基-嘧啶-4-基)-哌啶-4-基胺盐酸盐
4-Heptanone, 1,7-bis[bis(1-methylethyl)amino]-3,5-diphenyl-3,5-di-2-pyridinyl-
1-[2-fluoro-6-(2-methoxy-4-methylphenoxy)phenyl]ethan-1-amine
Ropinirole Related Compound A (50 mg) (4-(2-hydroxyethyl)indolin-2-one)
N-{2-[2-(sec-Butyl)phenoxy]ethyl}-2-isopropylaniline
2-(氨甲基)-1H苯并[d]咪唑-6-羧酸盐酸盐
1-(6-乙氧基-2-甲硫基-嘧啶-4-基)-哌啶-4-基胺盐酸盐
4-Heptanone, 1,7-bis[bis(1-methylethyl)amino]-3,5-diphenyl-3,5-di-2-pyridinyl-
1-[2-fluoro-6-(2-methoxy-4-methylphenoxy)phenyl]ethan-1-amine
Ropinirole Related Compound A (50 mg) (4-(2-hydroxyethyl)indolin-2-one)