4-methyl-2-(methylsulfonyl)pyrimidine - Names and Identifiers
4-methyl-2-(methylsulfonyl)pyrimidine - Physico-chemical Properties
Molecular Formula | C6H8N2O2S
|
Molar Mass | 172.2 |
Density | 1.285±0.06 g/cm3(Predicted) |
Boling Point | 346.9±35.0 °C(Predicted) |
pKa | -2.86±0.20(Predicted) |
Storage Condition | 2-8°C |
4-methyl-2-(methylsulfonyl)pyrimidine - Risk and Safety
4-methyl-2-(methylsulfonyl)pyrimidine - Introduction
Pyrimidine, 4-methyl-2-(methylsulfonyl)-is an organic compound with the chemical formula C7H10N2O2S. It is a white solid powder, soluble in organic solvents such as ethanol and dichloromethane, but insoluble in water.
The compound has a variety of applications. The most important use is as a pharmaceutical intermediate, especially for the synthesis of anti-cancer drugs and antiviral drugs. It plays an important role in the synthesis of nucleoside antiviral drugs such as acyclovir (Acyclovir), Lynchtine (Lentinan) and Sitafloxacin. In addition, it can also be used as research and laboratory medicine.
There are many methods for preparing Pyrimidine, 4-methyl-2-(methylsulfonyl)-. The common method is to start with 4-methyl-2-nitropyrimidine. First, 4-methyl-2-nitropyrimidine is reacted with sulfuric acid and nitric acid to form the corresponding sulfate. The sulfate salt is then reacted with methanol to give 4-methyl -2-carbinol pyrimidine. Finally, 4-methyl-2-methanol pyrimidine is reacted with benzenesulfonyl chloride to give Pyrimidine, 4-methyl-2-(methylsulfonyl)-.
Regarding safety information, Pyrimidine, 4-methyl-2-(methylsulfonyl)-is a harmful chemical substance that may cause irritation and damage to the human body. Appropriate protective measures should be taken during use and handling, such as wearing protective clothing, respirators and goggles. Avoid contact with skin and eyes, and make sure to operate in a well-ventilated place. If touched or inhaled, flush the affected area immediately with water and seek medical attention. At the same time, waste and pollutants should be properly disposed of and relevant safety procedures should be followed.
Last Update:2024-04-09 21:11:58