4-anilino-3-(methylamino)butan-1-ol

4-anilino-3-(methylamino)butan-1-ol - Names and Identifiers

Name	(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol
Synonyms	1,1-Diphenyl-L-valinol 4-anilino-3-(methylamino)butan-1-ol )-2-Amino-3-methyl-1,1-diphenyl-1-butanol (s)-2-amino-1,1-diphenyl-3-methyl-1-butanol (2S)-2-Amino-3-methyl-1,1-diphenylbutan-1-ol (S)-(-)-2-AMINO-3-METHYL-1,1-DIPHENYL-1-BUTANOL (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol Benzenemethanol, alpha-[(1S)-1-amino-2-methylpropyl]-alpha-phenyl- (S)-2-Amino-1,1-diphenyl-3-methyl-1-butanol, 1,1-Diphenyl-L-valinol
CAS	78603-95-9
InChI	InChI=1/C17H21NO/c1-13(2)16(18)17(19,14-9-5-3-6-10-14)15-11-7-4-8-12-15/h3-13,16,19H,18H2,1-2H3/t16-/m0/s1

4-anilino-3-(methylamino)butan-1-ol - Physico-chemical Properties

Molecular Formula	C17H21NO
Molar Mass	255.36
Density	1.074±0.06 g/cm3(Predicted)
Melting Point	95-99°C(lit.)
Boling Point	424.7±40.0 °C(Predicted)
Flash Point	210.6°C
Vapor Presure	5.73E-08mmHg at 25°C
pKa	11.20±0.50(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.576
MDL	MFCD01318248

4-anilino-3-(methylamino)butan-1-ol - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29062990

4-anilino-3-(methylamino)butan-1-ol - Introduction

(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol, also known as (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol, is a chiral compound. It has the following properties:

Appearance: Colorless to light yellow solid
Molecular formula: C18H21NO
Molecular weight: 267.37g/mol
melting point: 80-82 ℃
Boiling point: 410 ℃ (predicted value)
Density: 1.08g/cm³

(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol has a wide range of applications, including drug synthesis, chiral catalysts and optically active reagents. It can be used to synthesize compounds with pharmaceutical activity, especially for the preparation of chiral drugs. In addition, it can also be used as a chiral catalyst to promote specific chemical reactions in organic synthesis; at the same time, it also has applications in optically active reagents and asymmetric synthesis.

The method of preparing (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol is usually by reacting as follows:

(S)-2-amino-1-butene and dimethyl benzene dicarbonate are subjected to an addition reaction to obtain (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol.

With regard to safety information, specific toxicity and hazard assessments of this compound are rarely reported, and therefore laboratory safety practices should be strictly followed. (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol may be irritating to the skin and eyes, so contact with skin and eyes should be avoided during operation. In case of accidental contact, immediately flush the affected area with plenty of water and seek professional medical help. During handling and storage, avoid contact with oxidants, strong acids and alkalis to avoid fire or explosion.

Last Update：2024-04-09 21:11:58