4-Nitrophenylacetylene - Names and Identifiers
4-Nitrophenylacetylene - Introduction
4-Nitrophenylacetylene is an organic compound with the chemical formula C8H5NO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 4-Nitrophenylacetylene is a pale yellow crystal or powder.
-Melting point: about 105-106 ℃.
-Boiling point: about 306-307 ℃.
-Soluble: Soluble in some non-polar solvents, such as benzene and dimethylformamide.
Use:
- 4-Nitrophenylacetylene is widely used in organic synthesis reactions, such as coupling reactions, selective reduction, hydrogenation reactions, etc.
-It can also be used as an intermediate for the synthesis of drugs, dyes and polymer compounds.
Preparation Method:
4-Nitrophenylacetylene is usually synthesized by the following steps:
1. Under alkaline conditions, nitrobenzene hydrocarbon reacts with malonic anhydride to produce nitrophenyl malonate.
2. reaction of nitrophenyl malonate with an acetylene salt of an alkali metal to generate 4-Nitrophenylacetylene.
Safety Information:
- 4-Nitrophenylacetylene may be toxic to humans and may be irritating to the eyes, skin and respiratory tract. Wear appropriate protective equipment, such as goggles, gloves and respiratory protectors.
-It should be kept away from fire and oxidant and stored in a closed container.
-Do not contact with flammable substances, acids and alkalis.
-During use and storage, care should be taken to prevent reaction with water or moisture.
Last Update:2024-04-09 02:00:50