4-Methyl-2-(pyridin-3-yl) - Names and Identifiers
4-Methyl-2-(pyridin-3-yl) - Physico-chemical Properties
Molecular Formula | C10H8N2OS
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Molar Mass | 204.25 |
Density | 1.287 |
Melting Point | 125-131.5℃ |
Boling Point | 399℃ |
Flash Point | 195℃ |
Storage Condition | 2-8°C |
4-Methyl-2-(pyridin-3-yl) - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S22 - Do not breathe dust.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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4-Methyl-2-(pyridin-3-yl) - Introduction
4-Methyl-2-pyrid-3-yl-1,3-thiazole-5-carbaldehyde is an organic compound with the chemical formula C12H9N3OS. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: It is a white to yellowish crystal or crystalline solid.
2. melting point: its melting point is about 116-118 degrees Celsius.
3. Solubility: It dissolves in some organic solvents such as alcohols, ethers and ketones, but has poor solubility in water.
Use:
4-Methyl-2-pyrid-3-yl-1,3-thiazole-5-carbaldehyde is an important intermediate compound, which is often used in organic synthesis reactions, such as in the preparation of drugs, pesticides and other biologically active compounds.
Preparation Method:
The preparation method of 4-Methyl-2-pyrid-3-yl-1,3-thiazole-5-carbaldehyde can be carried out by the following steps:
1. first, 2-chloro -4-methyl -5-pyridine sulfur amidine and pyrrolidone are reacted to obtain 4-methyl -2-(3-pyridyl) thiazole.
2. Then, 4-methyl -2-(3-pyridyl) thiazole is reacted with sodium hydroxide and formaldehyde under appropriate reaction conditions to form 4-Methyl-2-pyrid-3-yl-1,3-thiazole-5-carbaldehyde.
Safety Information:
When using and handling 4-Methyl-2-pyrid-3-yl-1,3-thiazole-5-carbaldehyde, the following safety precautions need to be observed:
1. It may cause irritation to the eyes, skin and respiratory system, so it is necessary to wear appropriate personal protective equipment, such as protective glasses, protective gloves and respiratory protective equipment.
2. Avoid inhaling its dust or contacting its solution during operation to avoid discomfort.
3. during storage and use, it should be kept in a sealed container, away from high temperature, open flame and oxidant and other dangerous substances.
4. If the compound is accidentally exposed or inhaled, the corresponding area should be thoroughly cleaned immediately and medical help should be sought if necessary.
Last Update:2024-04-09 20:49:11