4-HYDROXY-6-METHYLCOUMARIN - Names and Identifiers
4-HYDROXY-6-METHYLCOUMARIN - Physico-chemical Properties
Molecular Formula | C10H8O3
|
Molar Mass | 176.17 |
Density | 1.372±0.06 g/cm3(Predicted) |
Melting Point | 261-264 °C (lit.) |
Boling Point | 359.7±42.0 °C(Predicted) |
Appearance | White to pink powder or crystal |
Color | White |
Maximum wavelength(λmax) | ['309nm(EtOH aq.)(lit.)'] |
pKa | 4.50±1.00(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
MDL | MFCD00085738 |
4-HYDROXY-6-METHYLCOUMARIN - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
HS Code | 29322985 |
Hazard Class | IRRITANT |
4-HYDROXY-6-METHYLCOUMARIN - Reference
Reference Show more | 1. Chapter Glacier, Luo Jinxiang, Lai Ting, etc. Study on the contact killing activity and quantitative structure-activity relationship of coumarin compounds against spider mite cinnabar [J]. Chinese Journal of pesticide science, 2016, 23 (1):37-48. |
4-HYDROXY-6-METHYLCOUMARIN - Introduction
4-Hydroxy-6-Methylcoumarin is an organic compound with the chemical formula C10H8O3, and its structure contains a hydroxyl group and a methyl group. It is a pale yellow crystalline solid with a distinctive aroma.
4-Hydroxy-6-Methylcoumarin is commonly used in the fields of fluorescent dyes, synthetic chemistry and medicine. It can emit fluorescence in the ultraviolet region through the absorption spectrum, so it is widely used in fluorescent probes, fluorescent dyes, labels and other applications. In addition, it can also be used to synthesize other active organic compounds, such as antibacterial agents, antioxidants and fluorescent developers.
The method of preparing 4-Hydroxy-6-Methylcoumarin is to react 4-methylcoumarin with an appropriate amount of sodium hydroxide in alcohol through hydroxylation reaction. Commonly used solvents are methanol or ethanol. The reaction temperature is generally in the range of 60-80°C, and a certain time is usually required to achieve the best yield.
When using 4-Hydroxy-6-Methylcoumarin, you need to pay attention to the following safety information: It is irritating and should avoid contact with skin and eyes. Wear protective equipment such as gloves, glasses and lab coat during use. At the same time, store in a dry, cool place, and avoid contact with oxidants and high temperature. When waste is disposed of, it should be disposed of in accordance with local environmental regulations. Most importantly, correct laboratory operating procedures must be followed to ensure the safety of the human body and the environment.
Last Update:2024-04-09 21:11:58