4-Chloro-1H-pyrrole-2-carbonitrile - Names and Identifiers
4-Chloro-1H-pyrrole-2-carbonitrile - Physico-chemical Properties
Molecular Formula | C5H3ClN2
|
Molar Mass | 126.54 |
Storage Condition | 2-8°C |
Sensitive | IRRITANT |
MDL | MFCD12923750 |
4-Chloro-1H-pyrrole-2-carbonitrile - Introduction
It is an organic compound with the chemical formula C5H3ClN. It is a white crystalline solid, not easily soluble in water, soluble in organic solvents such as ethanol, ether and dichloromethane.
It has a wide range of applications in the field of drugs and pesticides. It can be used as a pharmaceutical intermediate for the synthesis of various bioactive compounds, such as anticancer drugs and antibiotics. In addition, it can also be used as an important intermediate of pesticides, for the synthesis of pesticides and herbicides.
The preparation method can be carried out by a cyanation reaction and a chlorination reaction. First, pyrrole is reacted with hydrocyanic acid to obtain 4-cyano-1H-pyrrole, and then chlorination is carried out with chlorinating agent to convert 4-cyano-1H-pyrrole into calcium.
Regarding safety information, it is generally stable under normal use conditions. However, it can be irritating to the eyes, skin and respiratory tract. Therefore, appropriate protective equipment such as gloves, goggles and protective clothing should be worn during operation. At the same time, it should be operated in a well-ventilated place to avoid inhalation of vapor. If exposed or inhaled, wash the affected area immediately and seek medical help.
Last Update:2024-04-09 21:11:58