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4-Amino-2-(trifluoromethyl)benzoic acid

4-amino-2-(trifluoromethyl)benzoic acid

CAS: 393-06-6

Molecular Formula: C8H6F3NO2

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4-Amino-2-(trifluoromethyl)benzoic acid - Names and Identifiers

Name 4-amino-2-(trifluoromethyl)benzoic acid
Synonyms QVR DZ BXFFF
RARECHEM AL BO 0438
4-Amino-2-Trifluoromethylbenzo
2-trifluoromethyl-4-aminobenzoate
4-Amino-2-trifluoromethylbenzoicacid
4-Amino-α,α,α-trifluoro-o-toluic acid
4-AMINO-2-TRIFLUOROMETHYLBENZOIC ACID
4-amino-2-(trifluoromethyl)benzoic acid
4-Amimo-2-(trifluoro methyl) benzoic acid
Benzoic acid, 4-amino-2-(trifluoromethyl)-
CAS 393-06-6
InChI InChI=1/C8H6F3NO2/c9-8(10,11)6-3-4(12)1-2-5(6)7(13)14/h1-3H,12H2,(H,13,14)

4-Amino-2-(trifluoromethyl)benzoic acid - Physico-chemical Properties

Molecular FormulaC8H6F3NO2
Molar Mass205.13
Density1.489±0.06 g/cm3(Predicted)
Melting Point183-186℃
Boling Point318.8±42.0 °C(Predicted)
Flash Point146.622°C
Solubility soluble in Methanol
Vapor Presure0mmHg at 25°C
Appearancepowder to crystal
ColorWhite to Orange to Green
pKa3.89±0.36(Predicted)
Storage ConditionKeep in dark place,Inert atmosphere,Room temperature
Refractive Index1.528
MDLMFCD03407959

4-Amino-2-(trifluoromethyl)benzoic acid - Risk and Safety

Risk Codes22 - Harmful if swallowed
Hazard NoteHarmful
Hazard ClassIRRITANT

4-Amino-2-(trifluoromethyl)benzoic acid - Introduction

4-amino-2-(trifluoromethyl)benzoic acid is an organic compound with the chemical formula C8H6F3NO2.

Nature:
-Appearance: White crystalline solid
-Melting point: 181-185°C
-Solubility: Soluble in acidic and neutral solvents, slightly soluble in water

Use:
-Pharmaceutical applications: 4-amino-2-(trifluoromethyl)benzoic acid can be used as non-steroidal anti-inflammatory drugs and pain relief raw materials.
-Pesticide application: It can also be used as a raw material for pesticides, fungicides and herbicides.

Preparation Method:
4-amino-2-(trifluoromethyl)benzoic acid can be obtained by reacting benzoic acid in the presence of trifluoromethyl chloride (Trifluoromethyl chloride). First, benzoic acid and trifluoromethyl chloride are condensed in the presence of a base to obtain 4-amino-2-(trifluoromethyl)benzoic acid.

Safety Information:
-Due to the lack of sufficient toxicity data and safety assessment, appropriate chemical protective measures should be taken when using the compound, and direct contact with skin and eyes is strictly prohibited.
-Avoid dust and inhalation of the compound during operation. If exposed or inhaled, seek medical help immediately.
Last Update:2024-04-09 21:04:16
4-Amino-2-(trifluoromethyl)benzoic acid
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CAS: 393-06-6
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