4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylMethyl)-1H-pyrazole - Names and Identifiers
Name | 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-trityl-1H-pyrazole
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Synonyms | 1-Trityl-1H-pyrazole-4-boronic acid pinacol ester 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-trityl-1H... 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-trityl-pyrazole 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-trityl-1H-pyrazole 4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylMethyl)-1H-pyrazole 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylmethyl)pyrazole 1H-Pyrazole, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylmethyl)-
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CAS | 863238-73-7
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InChI | InChI=1/C28H29BN2O2/c1-26(2)27(3,4)33-29(32-26)25-20-30-31(21-25)28(22-14-8-5-9-15-22,23-16-10-6-11-17-23)24-18-12-7-13-19-24/h5-21H,1-4H3 |
4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylMethyl)-1H-pyrazole - Physico-chemical Properties
Molecular Formula | C28H29BN2O2
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Molar Mass | 436.35 |
Density | 1.07±0.1 g/cm3 (20 ºC 760 Torr) |
Boling Point | 587.3±50.0 °C(Predicted) |
pKa | 1.37±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.575 |
4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylMethyl)-1H-pyrazole - Introduction
4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-trityl-1H-pyrazole (abbreviated TMDP) is an organic compound. The following is a presentation of information on the nature, use, formulation and safety of the TMDP:
Nature:
TMDP is a solid compound with a white to light yellow appearance. It has high thermal and chemical stability, insoluble in water, but soluble in some organic solvents.
Use:
TMDP is widely used in organic synthesis, mainly as a raw material for ligands or catalysts. It can participate in many organic reactions, such as metal-catalyzed cross-coupling reactions, reduction reactions and Grignard reactions. TMDP can also be used for other purposes in organic synthesis, such as building carbon-nitrogen, carbon-boron, and carbon-oxygen bonds, among others.
Preparation Method:
The preparation of TMDP generally adopts the method of organic synthesis. One common method is by reacting the corresponding substituted benzoxazole with a boronic ester. The specific preparation steps and conditions can be adjusted and optimized according to the actual situation.
Safety Information:
Although TMDP has good solubility in some organic solvents, it is still an organic compound, so it is necessary to pay attention to safe operation when using it. TMDP may be irritating to the skin and eyes, so direct contact should be avoided when used. In the process of operation, should be equipped with appropriate labor protection equipment, such as laboratory gloves, goggles and protective clothing. In addition, TMDP should be stored away from fire and high temperature, and stored in dark conditions. Under normal operation, TMDP does not produce significant hazardous or highly toxic properties. However, in order to ensure safety, the product safety manual should be read carefully before use, and the operation and handling should be carried out in accordance with the correct operating procedures.
Last Update:2024-04-09 20:52:54