Benzoxazole, 4-(bromomethyl)-is an organic compound with the chemical formula C9H7BrNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Benzoxazole, 4-(bromomethyl)-colorless to pale yellow crystalline solid.
-Melting point: about 72-74°C.
-Boiling point: About 265-267 ℃.
-Low solubility in water, soluble in organic solvents such as ethanol and dichloromethane.
Use:
- Benzoxazole, 4-(bromomethyl)-is often used as a reagent, intermediate and functional material.
-In organic synthesis, it can be used to synthesize other nitrogen heterocyclic compounds or biologically active organic compounds.
Method:
- Benzoxazole, 4-(bromomethyl)-can be synthesized by the following steps:
1. O-Bromo toluene reacts with alkaline sodium carbonate to generate the corresponding Bromo benzyl alcohol.
2. The brominated benzyl alcohol reacts with ammonia to generate Benzoxazole, 4-(bromomethyl)-.
Safety Information:
- Benzoxazole, 4-(bromomethyl)-relatively stable under normal conditions of use. However, it may have an irritating effect on the skin, eyes and respiratory system. Therefore, appropriate protective measures should be taken during operation, such as wearing protective glasses, gloves and masks.
-Due to its potential toxicity, it should be sealed and stored away from fire and oxidizing agents.
-Follow laboratory safety practices when handling the compound and dispose of waste properly.