4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯
DLin-M-C3-DMA
CAS: 1224606-06-7
Molecular Formula: C43H79NO2
4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Names and Identifiers
4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Physico-chemical Properties
| Molecular Formula | C43H79NO2 |
| Molar Mass | 642.09 |
| Density | 0.886±0.06 g/cm3(Predicted) |
| Boling Point | 670.2±43.0 °C(Predicted) |
| Solubility | DMSO : ≥ 43.33 mg/mL (67.48 mM) ; Ethanol : 16.67 mg/mL (25.96 mM; Need ultrasonic) |
| pKa | 9.37±0.28(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Physical and Chemical Properties | Bioactive D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is an effective and ionizable cationic liposome. D-Lin-MC3-DMA is used to deliver siRNA in vivo. |
| Use | The chemical name of the DLIN-M-C3-DMA is 4-(N,N-dimethylamine) butyric acid -6,9,28, 31-tetraene-19-trimetanol ester, which can be used to prepare liposome preparations. Liposome preparations include complementary double positive lipids, phospholipids and long-acting lipids. Complementary double positive lipids include: the first positive lipid and the second positive lipid. DLIN-M-C3-DMA can be used as the first positive lipid. |
4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Upstream Downstream Industry
4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.557 ml | 7.787 ml | 15.574 ml |
| 5 mM | 0.311 ml | 1.557 ml | 3.115 ml |
| 10 mM | 0.156 ml | 0.779 ml | 1.557 ml |
| 5 mM | 0.031 ml | 0.156 ml | 0.311 ml |
Last Update：2024-01-02 23:10:35
4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Introduction
DLin-M-C3-DMA, also known as DMBAE, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: DMBAE is a colorless liquid
-Molecular formula: C13H25NO2
-Molecular weight: 227.34g/mol
-Melting point:-30 ° C
-Boiling point: 318-332 ° C
-Density: 0.956 g/mL
Use:
- DMBAE is widely used in coatings and adhesives as a plasticizer.
-It can also be used as a reactive diluent, which can reduce the viscosity of the coating and chemically react with other compounds during the curing process.
Preparation Method:
- DMBAE is generally prepared by an acid-catalyzed alcohol amine reaction. First, dioleyl methanol and 4-(N,N-dimethylamino) butyric acid are mixed in a suitable solvent at a molar ratio of 1:1. Under the action of a catalyst, the reaction is heated, generate DMBAE.
Safety Information:
- DMBAE is a flammable liquid, away from fire and high temperature environment.
-Avoid direct contact with skin and eyes, and take personal protective measures, such as glasses, gloves and protective clothing, if necessary.
-Pay attention to ventilation during operation and avoid contact with strong oxidants.
-If inhalation or skin contact occurs, immediately stay away from the source, wash the affected area, and seek medical help.
-please read the product safety data sheet (SDS) before use.
Nature:
-Appearance: DMBAE is a colorless liquid
-Molecular formula: C13H25NO2
-Molecular weight: 227.34g/mol
-Melting point:-30 ° C
-Boiling point: 318-332 ° C
-Density: 0.956 g/mL
Use:
- DMBAE is widely used in coatings and adhesives as a plasticizer.
-It can also be used as a reactive diluent, which can reduce the viscosity of the coating and chemically react with other compounds during the curing process.
Preparation Method:
- DMBAE is generally prepared by an acid-catalyzed alcohol amine reaction. First, dioleyl methanol and 4-(N,N-dimethylamino) butyric acid are mixed in a suitable solvent at a molar ratio of 1:1. Under the action of a catalyst, the reaction is heated, generate DMBAE.
Safety Information:
- DMBAE is a flammable liquid, away from fire and high temperature environment.
-Avoid direct contact with skin and eyes, and take personal protective measures, such as glasses, gloves and protective clothing, if necessary.
-Pay attention to ventilation during operation and avoid contact with strong oxidants.
-If inhalation or skin contact occurs, immediately stay away from the source, wash the affected area, and seek medical help.
-please read the product safety data sheet (SDS) before use.
Last Update：2024-04-10 22:29:15
Supplier List
Featured ProductsSpot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Featured ProductsSpot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Multiple SpecificationsSpot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Featured ProductsSpot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Featured ProductsSpot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Multiple SpecificationsSpot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯
Carbamothioic acid, dimethyl-, S-(4-acetyl-3-hydroxy-2-propylphenyl) ester (9CI)
N-ALPHA-BOC-D-2,4-DIAMINOBUTYRIC ACID
5-alpha-h-tropan-3-alpha-ol,6-beta,7-beta-epoxy-1-alpha-(-)-tropate(est
N-Alpha-T-Boc-L-Arginine Monohydrochloride Monohydrate
5-异丙基-2-溴噻唑
potassiuM (4-cyanophenyl)(trifluoro)borate(1-)
Benzeneethanamine,4-chloro-N,a,a-trimethyl-, hydrochloride (1:1)
Ethanone, 1-bicyclo[4.2.0]octa-2,4-dien-7-yl-, (1alpha,6alpha,7alpha)- (9CI)
邻磺酰胺苯甲酸甲酯
Carbamothioic acid, dimethyl-, S-(4-acetyl-3-hydroxy-2-propylphenyl) ester (9CI)
N-ALPHA-BOC-D-2,4-DIAMINOBUTYRIC ACID
5-alpha-h-tropan-3-alpha-ol,6-beta,7-beta-epoxy-1-alpha-(-)-tropate(est
N-Alpha-T-Boc-L-Arginine Monohydrochloride Monohydrate
5-异丙基-2-溴噻唑
potassiuM (4-cyanophenyl)(trifluoro)borate(1-)
Benzeneethanamine,4-chloro-N,a,a-trimethyl-, hydrochloride (1:1)
Ethanone, 1-bicyclo[4.2.0]octa-2,4-dien-7-yl-, (1alpha,6alpha,7alpha)- (9CI)
邻磺酰胺苯甲酸甲酯
Raw Materials for 4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯
6,9,28,31-Heptatriacontatetraen-19-ol, (6Z,9Z,28Z,31Z)-
4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE
CIS,CIS-9,12-OCTADECADIENOL
9,12-Octadecadien-1-ol, methanesulfonate, (9Z,12Z)-
4-(Dimethylamino)butanoic acid
4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE
CIS,CIS-9,12-OCTADECADIENOL
9,12-Octadecadien-1-ol, methanesulfonate, (9Z,12Z)-
4-(Dimethylamino)butanoic acid