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4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯

DLin-M-C3-DMA

CAS: 1224606-06-7

Molecular Formula: C43H79NO2

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4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Names and Identifiers

Name DLin-M-C3-DMA
Synonyms DLINMC3DMA
DLin-M-C3-DMA
D-LIN-MC3-DMA
D-Lin-MC3-DMA
D-LIN-MC-3-DMA
D-Lin-MC3-DMA (MC3)
dilinoleylmethyl 4-(dimethylamino)butanoate
O-(Z,Z,Z,Z-heptatriaconta-6,9,26,29-tetraen-19-yl)-4-(N,N-dimethylamino)
(6Z,9Z,28Z,31Z)-heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate
(6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate
Butanoic acid, 4-(dimethylamino)-, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester
CAS 1224606-06-7

4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Physico-chemical Properties

Molecular FormulaC43H79NO2
Molar Mass642.09
Density0.886±0.06 g/cm3(Predicted)
Boling Point670.2±43.0 °C(Predicted)
Solubility DMSO : ≥ 43.33 mg/mL (67.48 mM) ; Ethanol : 16.67 mg/mL (25.96 mM; Need ultrasonic)
pKa9.37±0.28(Predicted)
Storage ConditionSealed in dry,Room Temperature
Physical and Chemical PropertiesBioactive D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is an effective and ionizable cationic liposome. D-Lin-MC3-DMA is used to deliver siRNA in vivo.
UseThe chemical name of the DLIN-M-C3-DMA is 4-(N,N-dimethylamine) butyric acid -6,9,28, 31-tetraene-19-trimetanol ester, which can be used to prepare liposome preparations. Liposome preparations include complementary double positive lipids, phospholipids and long-acting lipids. Complementary double positive lipids include: the first positive lipid and the second positive lipid. DLIN-M-C3-DMA can be used as the first positive lipid.

4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Upstream Downstream Industry

Raw Materials6,9,28,31-Heptatriacontatetraen-19-ol, (6Z,9Z,28Z,31Z)-
4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE
CIS,CIS-9,12-OCTADECADIENOL
9,12-Octadecadien-1-ol, methanesulfonate, (9Z,12Z)-
4-(Dimethylamino)butanoic acid

4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Preparation solution concentration reference

 1mg5mg10mg
1 mM1.557 ml7.787 ml15.574 ml
5 mM0.311 ml1.557 ml3.115 ml
10 mM0.156 ml0.779 ml1.557 ml
5 mM0.031 ml0.156 ml0.311 ml
Last Update:2024-01-02 23:10:35

4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯 - Introduction

DLin-M-C3-DMA, also known as DMBAE, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: DMBAE is a colorless liquid
-Molecular formula: C13H25NO2
-Molecular weight: 227.34g/mol
-Melting point:-30 ° C
-Boiling point: 318-332 ° C
-Density: 0.956 g/mL

Use:
- DMBAE is widely used in coatings and adhesives as a plasticizer.
-It can also be used as a reactive diluent, which can reduce the viscosity of the coating and chemically react with other compounds during the curing process.

Preparation Method:
- DMBAE is generally prepared by an acid-catalyzed alcohol amine reaction. First, dioleyl methanol and 4-(N,N-dimethylamino) butyric acid are mixed in a suitable solvent at a molar ratio of 1:1. Under the action of a catalyst, the reaction is heated, generate DMBAE.

Safety Information:
- DMBAE is a flammable liquid, away from fire and high temperature environment.
-Avoid direct contact with skin and eyes, and take personal protective measures, such as glasses, gloves and protective clothing, if necessary.
-Pay attention to ventilation during operation and avoid contact with strong oxidants.
-If inhalation or skin contact occurs, immediately stay away from the source, wash the affected area, and seek medical help.
-please read the product safety data sheet (SDS) before use.
Last Update:2024-04-10 22:29:15
4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯
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CAS: 1224606-06-7
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CAS: 1224606-06-7
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View History
4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯
哌啶甲酸乙酯异构体
乙酸基氨基吡啶
4-氯-6-碘噻吩并[3,2-d]嘧啶
EC 3.1.4.12
6-甲酰基-1H-吲哚-1-甲酸叔丁酯
C.I. Reactive Brown 9
6-甲基噻吩并[2,3-D]嘧啶-4-醇
伐地那非杂质(2-乙氧基苄AM盐酸盐)
3-溴吡唑并[1,5-a]嘧啶-6-醇
Raw Materials for 4-(N,N-二甲基氨基)丁酸(二亚油基)甲酯
6,9,28,31-Heptatriacontatetraen-19-ol, (6Z,9Z,28Z,31Z)-
4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE
CIS,CIS-9,12-OCTADECADIENOL
9,12-Octadecadien-1-ol, methanesulfonate, (9Z,12Z)-
4-(Dimethylamino)butanoic acid
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