4-(4-Fluorophenyl)-1H-pyrazol-5-amine
(2E)-2-(6-methyl-1H-benzimidazol-2-yl)-3-[5-(1-oxo-1,3-dihydro-2-benzofuran-5-yl)furan-2-yl]prop-2-enenitrile
CAS: 5848-05-5
Molecular Formula: C9H8FN3
4-(4-Fluorophenyl)-1H-pyrazol-5-amine - Names and Identifiers
| Name | (2E)-2-(6-methyl-1H-benzimidazol-2-yl)-3-[5-(1-oxo-1,3-dihydro-2-benzofuran-5-yl)furan-2-yl]prop-2-enenitrile |
| Synonyms | 4-(4-FLUOROPHENYL)-1H-PYRAZOL-5-AMINE 4-(4-fluorophenyl)-2H-pyrazol-3-amine 4-(4-fluorophenyl)-1H-pyrazol-5-ylamine 4-(4-FLUORO-PHENYL)-2H-PYRAZO-3-YLAMINE [4-(4-fluorophenyl)-2H-pyrazol-3-yl]amine (2E)-2-(6-methyl-1H-benzimidazol-2-yl)-3-[5-(1-oxo-1,3-dihydro-2-benzofuran-5-yl)furan-2-yl]prop-2-enenitrile (2E)-2-(6-Methyl-1H-benziMidazol-2-yl)-3-[5-(1-oxo-1,3-dihydro-2-benzofuran-5-yl)furan-2-yl]prop-2-enenitrile |
| CAS | 5848-05-5 |
| InChI | InChI=1/C23H15N3O3/c1-13-2-6-19-20(8-13)26-22(25-19)15(11-24)10-17-4-7-21(29-17)14-3-5-18-16(9-14)12-28-23(18)27/h2-10H,12H2,1H3,(H,25,26)/b15-10+ |
4-(4-Fluorophenyl)-1H-pyrazol-5-amine - Physico-chemical Properties
| Molecular Formula | C9H8FN3 |
| Molar Mass | 177.18 |
| Density | 1.399g/cm3 |
| Melting Point | 174 °C |
| Boling Point | 705.5°C at 760 mmHg |
| Flash Point | 380.5°C |
| Vapor Presure | 9.4E-20mmHg at 25°C |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.725 |
4-(4-Fluorophenyl)-1H-pyrazol-5-amine - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Class | IRRITANT |
4-(4-Fluorophenyl)-1H-pyrazol-5-amine - Introduction
(2E)-2-(5-oxo-1)-3-[5-(1-oxo-1,) furan-2-yl]prop-2-enenitrile ((2E)-2-(6-methyl-1H-benzimidazol-2-yl)-3-[5-(1-oxo-1, 3-Dihydro-2-benzofuran-5-yl) furan-2-yl] propan-2-enenitrile), also known as DAB492, is an organic compound. Here is some information about DAB492:
Nature:
-Appearance: White to light yellow solid
-melting point: about 160-162 ℃
-Molecular formula: C29H18FNN3O3
-Molecular weight: 489.47g/mol
Use:
DAB492 has certain application value in pharmaceutical chemistry, mainly used to study anti-tumor activity and other biological activities, such as antibacterial activity. It is also used as a synthetic intermediate for the synthesis of other compounds.
Preparation Method:
The preparation method of DAB492 is complicated and involves multi-step reactions. One possible synthetic route involves several organic synthesis reactions, and the final product is obtained by repeating the reaction, purification and crystallization under specific conditions.
Safety Information:
The specific safety information for DAB492 may vary by country and region. Generally speaking, as a chemical substance, DAB492 needs to be handled in an appropriate chemical laboratory, wear appropriate personal protective equipment, and follow laboratory safety procedures. In addition, avoid contact with eyes, skin and administration, and avoid inhalation of dust or gas. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Please note that this information is provided for general reference only and that actual safety data and relevant regulations are required for specific situations. When using or handling DAB492, follow appropriate safety practices and recommendations.
Nature:
-Appearance: White to light yellow solid
-melting point: about 160-162 ℃
-Molecular formula: C29H18FNN3O3
-Molecular weight: 489.47g/mol
Use:
DAB492 has certain application value in pharmaceutical chemistry, mainly used to study anti-tumor activity and other biological activities, such as antibacterial activity. It is also used as a synthetic intermediate for the synthesis of other compounds.
Preparation Method:
The preparation method of DAB492 is complicated and involves multi-step reactions. One possible synthetic route involves several organic synthesis reactions, and the final product is obtained by repeating the reaction, purification and crystallization under specific conditions.
Safety Information:
The specific safety information for DAB492 may vary by country and region. Generally speaking, as a chemical substance, DAB492 needs to be handled in an appropriate chemical laboratory, wear appropriate personal protective equipment, and follow laboratory safety procedures. In addition, avoid contact with eyes, skin and administration, and avoid inhalation of dust or gas. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Please note that this information is provided for general reference only and that actual safety data and relevant regulations are required for specific situations. When using or handling DAB492, follow appropriate safety practices and recommendations.
Last Update：2024-04-09 20:52:54
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